Találati lista | Tudóstér

001-es BibID:	BIBFORM102721
035-os BibID:	(Scopus)85137125116
Első szerző:	Képes Zita (orvos)
Cím:	Initial clinical experience with dedicated multi-pinhole (MPH) collimator for 99mTc-HMPAO brain perfusion SPECT / Zita Képes, Kornél Kukuts, Attila Oszlánszki, Iván Mihovk, Áron Krizsán, Sándor Barna, Andrew Robinson, Daniel Deidda, János Mester, József Varga, Ildikó Garai, Attila Forgács
Dátum:	2022
ISSN:	1790-5427
Megjegyzések:	Abstract Objective: Dedicated multi-pinhole (MPH) collimators have been successfully tested in selected clinical investigations. The aim of our work was to report initial experiences with an MPH collimator set designed for brain perfusion single photon emission tomography (SPECT). Methods: Ten patients underwent sequential technetium-99m-hexamethylpropyleneamineoxime (99mTc-HMPAO) SPECT with a dual-head SPECT camera equipped with conventional low-energy parallel hole collimators (LEHR), and with a triple-head system equipped with MPH collimators. Low-energy parallel hole collimators data were reconstructed by filtered back projection (FBP), ordered subset expectation maximization (OSEM), software for tomographic image reconstruction (STIR). In addition, both the parallel hole data and MPH data were reconstructed by Tera-TomoTM 3D iterative reconstruction denoted LEHR_TT3D and MPH_TT3D, respectively. Five medical experts visually compared the reconstructed images of the five data sets and defined a ranking sequence from the lowest (1) to the highest (5) image quality. Results were compared using the Friedman test. P values below 0.05 were considered significant. Results: Low-energy parallel hole collimators acquisition resulted in 5 million, while MPH acquisition in 13 million total counts with 30 and 34 minutes of acquisition time, respectively. Mean rank coefficients of the reconstruction methods were 1.96?0.52, 2.66?0.46, 2.86?0.60, 3.62?0.55, 3.9?0.68 for FBP, STIR, LEHR_TT3D, LEHR_OSEM, MPH_TT3D respectively. The differences between MPH_TT3D-FBP (P<0.01); MPH_TT3D-STIR (P<0.05); LEHR_OSEM-FBP (P<0.01) were significant. Conclusion: Image quality provided by MPH collimator is comparable to that provided by conventional LEHR imaging. Higher sensitivity has the potential to shorten acquisition time or to reduce the amount of administered activity.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Brain perfusion SPECT Multi-pinhole collimator Reconstruction Image quality
Megjelenés:	Hellenic Journal of Nuclear Medicine. - 25 : 2 (2022), p. 143-147. -
További szerzők:	Kukuts Kornél Oszlánszki Attila Mihovk Iván Krizsán Áron Krisztián (1986-) (fizikus) Barna Sándor (1982-) (kutató orvos) Robinson, Andrew Deidda, Daniel Mester János Varga József (1955-) (fizikus) Garai Ildikó (1966-) (radiológus) Forgács Attila (1985-) (fizikus)
Pályázati támogatás:	National Grant No. GINOP-2.1.1-15-2015-00609 GINOP UK National Physical Laboratory through the National Measurement System Egyéb
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
Borító:
Saját polcon:

001-es BibID:	BIBFORM110191
035-os BibID:	(wos)000957376600001 (scopus)85150973802
Első szerző:	Krizsán Áron Krisztián (fizikus)
Cím:	Performance evaluation of a novel multi-pinhole collimator on triple-NaI-detector SPECT/CT for dedicated myocardial imaging / Krizsan Aron K., Kukuts Kornel, Al-Muhanna Walid, Szoboszlai Zoltan, Balazs Laszlo, Szabo Balazs, Kiss Janos, Nekolla Stephan, Barna Sandor, Garai Ildiko, Bukki Tamas, Forgacs Attila
Dátum:	2023
ISSN:	2197-7364
Megjegyzések:	Background: In this study we evaluated the imaging capabilities of a novel Multipinhole collimator (MPH-Cardiac) specially designed for nuclear cardiology imaging on a Triple-NaI-detector based SPECT/CT system. Methods: 99mTc point source measurements covering the field of view (FOV) were used to determine tomographic sensitivity ( TSpointsource) and spatial resolution. Organsize tomographic sensitivity ( TSorgan) was measured with a left ventricle (LV) phantom filled with typical myocardial activity of a patient scan. Reconstructed image uniformity was measured with a 140 mm diameter uniform cylinder phantom. Using the LV phantom once filled with 99mTc and after with 123I, Contrast-to-noise ratio (CNR) was measured on the reconstructed images by ROI analysis on the myocardium activity and on the LV cavity. Furthermore, a polar map analysis was performed determining Spill-Over-Ratio in water ( SORwater) and image noise. The results were compared with that of a dual-head parallel-hole low energy high resolution (LEHR) collimator system. A patient with suspected coronary artery disease (CAD) was scanned on the LEHR system using local protocol of 16 min total acquisition time, followed by a 4-min MPH-Cardiac scan. Results: Peak TSpointsource was found to be 1013 cps/MBq in the axial center of the FOV while it was decreasing toward the radial edges. TSorgan in the CFOV was found to be 134 cps/MBq and 700 cps/MBq for the LEHR and MPH-Cardiac, respectively. Average spatial resolution throughout the FOV was 4.38 mm FWHM for the MPH-Cardiac collimator. Reconstructed image uniformity values were found to be 0.292% versus 0.214% for the LEHR and MPH-Cardiac measurements, respectively. CNR was found to be higher in case of MPH-Cardiac than for LEHR in case of 99mTc (15.5 vs. 11.7) as well as for 123I (13.5 vs. 8.3). SORwater values were found to be 28.83% and 21.1% for the 99mTc measurements, and 31.44% and 24.33% for the 123I measurements for LEHR and MPHCardiac, respectively. Pixel noise of the 99mTc polar maps resulted in values of 0.38% and 0.24% and of the 123I polar maps 0.62% and 0.21% for LEHR and MPH-Cardiac, respectively. Visually interpreting the patient scan images, MPH-Cardiac resulted in better image contrast compared to the LEHR technique with four times shorter scan duration.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	EJNMMI Physics. - 10 : 1 (2023), p. 1-16. -
További szerzők:	Kukuts Kornél Al-Muhanna, Walid Szoboszlai Zoltán (1980-) (fizikus) Balázs László (fizikus) Szabó Balázs (1991-) (általános orvos) Kiss János (1992-) (fizikus) Nekolla, Stephan Barna Sándor (1982-) (kutató orvos) Garai Ildikó (1966-) (radiológus) Bükki Tamás Forgács Attila (1985-) (fizikus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM098813
035-os BibID:	(WoS)000631148700002 (Scopus)85102729201
Első szerző:	Nagy Ferenc (fizikus)
Cím:	Q-Bot: automatic DICOM metadata monitoring for the next level of quality management in nuclear medicine / Nagy Ferenc, Krizsan Aron K., Kukuts Kornél, Szolikova Melinda, Hascsi Zsolt, Barna Sandor, Acs Antonietta, Szabo Peter, Tron Lajos, Balkay Laszlo, Dahlbom Magnus, Zentai Mihaly, Forgacs Attila, Garai Ildiko
Dátum:	2021
ISSN:	2197-7364
Tárgyszavak:	Természettudományok Fizikai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	EJNMMI Physics. - 8 : 1 (2021), p. 1-13. -
További szerzők:	Krizsán Áron Krisztián (1986-) (fizikus) Kukuts Kornél Szolikova, Melinda Hascsi Zsolt Barna Sándor (1982-) (kutató orvos) Ács Antonietta Szabó Péter (nukleáris medicina szakorvos) Trón Lajos (1941-) (biofizikus) Balkay László (1963-) (biofizikus) Dahlbom, Magnus Zentai Mihaly Forgács Attila (1985-) (fizikus) Garai Ildikó (1966-) (radiológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM134394
Első szerző:	Ogum, A.
Cím:	Coronary Flow Reserve Evaluation with a Novel Multi-pinhole Collimator on Triple-Na-I-detector SPECT/CT in Coronary Artery Disease : a Pilot Study / Ogum A., Barna S., Szoboszlai Z., Krizsan A. K., Renaud J., Mitchell T., Budai Á., Ország G., Csikos C., Garai I.
Dátum:	2025
Megjegyzések:	Aim/Introduction: While PET/CT remains the standard for quantification of absolute myocardial blood flow (MBF) and coronary flow reserve (CFR), its clinical use is limited by cost and availability. Dynamic acquisition with dedicated cardiac SPECT systems has shown promise in addressing these issues, albeit with further research yet needed. This study aims to evaluate CFR using a novel multi-pinhole collimator on a Triple-NaI-detector SPECT/CT system (1) and correlate CFR data with the clinical pretest probability of coronary artery disease (CAD). Keywords: Coronary artery disease, Multi-pinhole collimator, Myocardial flow imaging, Coronary flow reserve, Myocardial blood flow Materials and Methods: Eleven patients (median age: 62) with known or suspected CAD underwent one-day stress-rest 99mTc-MIBI SPECT/ CT imaging using a multi-pinhole collimator system on a Triple-NaI- detector. Dynamic flow imaging followed rest and Regadenoson- induced stress phases. Images were reconstructed with a Monte Carlo-based algorithm for multi-pinhole projections. MBF and CFR were quantified using a dedicated software suite and compared with pretest CAD probability scores to assess diagnostic value. Results: No patient showed significant obstructive CAD (?70% stenosis) on angiography. CFR showed a moderate, though not statistically significant, positive correlation with CAD risk scores, r(7) = 0.62, p = 0.077, suggesting a potential physiological link between non-invasive flow data and baseline cardiovascular risk. Measured flow values were lower than those reported using other dedicated cardiac SPECT systems. (2) Conclusion: The multi-pinhole collimator on the Triple-NaI-detector SPECT/CT system yields reliable flow measurements that align with CAD risk scores, even in the absence of angiographic stenosis. This technique shows promise for early detection of microvascular dysfunction and may offer a cost- effective alternative to PET or other specialized SPECT systems.Further studies are needed to define diagnostic flow thresholds. References: 1)Krizsan AK, Kukuts K, Al-Muhanna W, Szoboszlai Z, Balazs L, Szabo B, Kiss J, Nekolla S, Barna S, Garai I, Bukki T, Forgacs A. Performance evaluation of a novel multi-pinhole collimator on triple-NaI-detector SPECT/CT for dedicated myocardial imaging.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk
Megjelenés:	EANM Innovation. - 1 (2025), p. S234. -
További szerzők:	Barna Sándor (1982-) (kutató orvos) Szoboszlai Zoltán (1980-) (fizikus) Krizsán Áron Krisztián (1986-) (fizikus) Renaud, J. Mitchell, T. Budai Ádám Ország Gábor Csikos Csaba (1997-) (orvos) Garai Ildikó (1966-) (radiológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: