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001-es BibID:BIBFORM112910
035-os BibID:(wos)001011827700001 (scopus)85162693630
Első szerző:Fuchs-Buder, Thomas
Cím:Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents : The 2023 Geneva revision / Fuchs-Buder Thomas, Brull Sorin J., Fagerlund Malin Jonsson, Renew Ross J., Cammu Guy, Murphy Glenn S., Warlé Michiel, Vested Matias, Fülesdi Béla, Nemes Reka, Columb Malachy O., Damian Daniela, Davis Peter J., Iwasaki Haijme, Eriksson Lars I.
Dátum:2023
ISSN:0001-5172
Megjegyzések:The set of guidelines for good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents was developed following an international consensus conference in Copenhagen in 1996 (Viby-Mogensen et al., Acta Anaesthesiol Scand 1996, 40, 59?74); the guidelines were later revised and updated following the second consensus conference in Stockholm in 2005 (Fuchs-Buder et al., Acta Anaesthesiol Scand 2007, 51, 789?808). In view of new devices and further development of monitoring technologies that emerged since then, (e.g., electromyography, three-dimensional acceleromyography, kinemyography) as well as novel compounds (e.g., sugammadex) a review and update of these recommendations became necessary. The intent of these revised guidelines is to continue to help clinical researchers to conduct high-quality work and advance the field by enhancing the standards, consistency, and comparability of clinical studies. There is growing awareness of the importance of consensus-based reporting standards in clinical trials and observational studies. Such global initiatives are necessary in order to minimize heterogeneous and inadequate data reporting and to improve clarity and comparability between different studies and study cohorts. Variations in definitions of endpoints or outcome variables can introduce confusion and difficulties in interpretation of data, but more importantly, it may preclude building of an adequate body of evidence to achieve reliable conclusions and recommendations. Clinical research in neuromuscular pharmacology and physiology is no exception.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
depth of neuromuscular blockade
neuromuscular monitoring
neuromuscular research
pharmacodynamics
postoperative pulmonary complications
time course of neuromuscular blockade
Megjelenés:Acta Anaesthesiologica Scandinavica. - 67 : 8 (2023), p. 994-1017. -
További szerzők:Brull, Sorin J. Fagerlund, Malin Jonsson Renew, J. Ross Cammu, Guy Murphy, Glenn S. Warlé, Michiel Vested, Matias Fülesdi Béla (1961-) (aneszteziológus) Nemes Réka (1985-) (aneszteziológus, intenzív terápiás szakorvos) Columb, Malachy O. Damian, Daniela Davis, Peter J. Iwasaki, Haijme Eriksson, Lars I.
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001-es BibID:BIBFORM094393
Első szerző:Renew, J. Ross
Cím:Belgian anesthesiologists' overconfidence in their perceived understanding of neuromuscular blockade management / Renew J. R., Nemes R., Cammu G., Van de Velde M., Brull S. J., Naguib M.
Dátum:2019
ISSN:0001-5164
Megjegyzések:Background : The incidence of postoperative residual weakness remains unacceptably high and essentially unchanged over decades. It is puzzling why anesthesiologists are resistant to accept the concepts of safe management of neuromuscular blockade and reversal. It appears that pervasive misconceptions regarding appropriate implementation of neuromuscular blockade monitoring and management continue to be a substantial obstacle in addressing this issue. Methods : We conducted a 10-question survey composed of true/false options to determine the respondents' knowledge regarding neuromuscular blockade management. Surveys were made available during an unannounced 90 minute period of a national anesthesiology conference in Belgium. Participants were also asked to rate their confidence in their responses. Results : One hundred and fifty-seven anesthesiologists (69 certified anesthesiologists and 88 anesthesiologistsin- training) completed the 10-question survey. Respondents were correct 72% of the time, yet rated their mean confidence significantly higher as 80%. Conclusions : The surveyed anesthesia providers conveyed overconfidence in their understanding of neuromuscular blockade management. Such misconceptions represent a substantial challenge to improving the standards of neuromuscular blockade management throughout the anesthesia community
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Neuromuscular blockade management
quantitative neuromuscular monitoring
postoperative residual weakness
misconception
overconfidence
Megjelenés:Acta Anaesthesiologica Belgica. - 70 (2019), p. 161-165. -
További szerzők:Nemes Réka (1985-) (aneszteziológus, intenzív terápiás szakorvos) Cammu, Guy Van de Velde, M. Brull, Sorin J. Naguib, Mohamed
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