CCL

Összesen 5 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM118762
035-os BibID:(cikkazonosító)1345877 (WoS)001175930800001 (Scopus)85186558578
Első szerző:Domán Marianna (biológus)
Cím:Genomic epidemiology of antifungal resistance in human and avian isolates of Candida albicans : a pilot study from the One Health perspective / Marianna Domán, Eszter Kaszab, Levente Laczkó, Krisztina Bali, László Makrai, Renátó Kovács, László Majoros, Krisztián Bányai
Dátum:2024
ISSN:2297-1769
Megjegyzések:Stress-induced genomic changes in Candida albicans contribute to the adaptation of this species to various environmental conditions. Variations of the genome composition of animal-origin C. albicans strains are largely unexplored and drug resistance or other selective pressures driving the evolution of these yeasts remained an intriguing question. Comparative genome analysis was carried out to uncover chromosomal aneuploidies and regions with loss of heterozygosity (LOH), two mechanisms that manage genome plasticity. We detected aneuploidy only in human isolates. Bird-derived isolates showed LOH in genes commonly associated with antifungal drug resistance similar to human isolates. Our study suggests that environmental fungicide usage might exert selective pressure on C. albicans infecting animals, thus contributing to the spread of potentially resistant strains between different hosts
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
yeast
aneuploidy
loss of heterozygosity
drug resistance
whole genome sequencing
Megjelenés:Frontiers in Veterinary Science. - 11 (2024), p. 1-7. -
További szerzők:Kaszab Eszter (1989-) (biológus) Laczkó Levente (1992-) (biológus) Bali Krisztina Makrai László Kovács Renátó László (1987-) (molekuláris biológus) Majoros László (1966-) (szakorvos, klinikai mikrobiológus) Bányai Krisztián
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM091231
Első szerző:Domán Marianna (biológus)
Cím:Molecular Diversity and Genetic Relatedness of Candida albicans Isolates from Birds in Hungary / Domán Marianna, Makrai László, Lengyel György, Kovács Renátó, Majoros László, Bányai Krisztián
Dátum:2021
ISSN:0301-486X
Megjegyzések:The molecular epidemiology of Candida albicans infections in animals has been rarely studied. In this study, multilocus sequence typing was used to characterise the genetic diversity and population structure of 24 avian origin C. albicans isolates collected from different birds with candidiasis and compared to human isolates. Fourteen diploid sequence types (DSTs) including six new DSTs were determined. Cluster analysis revealed that isolates grouped into 8 clades. Bird isolates mainly belonged to minor clades and Clade 15 with DST 172 was the most common (11 isolates; 45.8%). The remaining isolates were clustered into Clade 7 (5 isolates; 20.8%), Clade 10 (4 isolates; 16.6%), Clade 8 (2 isolates; 8.3%), Clade 4 (1 isolate; 4.2%) and Clade 16 (1 isolate; 4.2%). Unweighted pair group method with arithmetic averages (UPGMA) and eBURST analyses showed that the genetic construction of avian origin C. albicans population is fairly diverse. Although species-specific lineages were not found, some degree of separation in the evolution of bird and human strains could be observed.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Mycopathologia. - 186 : 2 (2021), p. 237-244. -
További szerzők:Makrai László Lengyel György Kovács Renátó László (1987-) (molekuláris biológus) Majoros László (1966-) (szakorvos, klinikai mikrobiológus) Bányai Krisztián
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM118511
035-os BibID:(WoS)001028622300001 (Scopus)85165039685 (cikkazonosító)2137
Első szerző:Gál Bence
Cím:Marked Genotype Diversity among Reoviruses Isolated from Chicken in Selected East-Central European Countries / Bence Gál, Renáta Varga-Kugler, Katalin Ihász, Eszter Kaszab, Marianna Domán, Szilvia Farkas, Krisztián Bányai
Dátum:2023
ISSN:2076-2615
Megjegyzések:The concern that the vaccines currently used against Avian orthoreovirus (ARV) infections are less efficient in the field justifies the need for the close monitoring of circulating ARV strains. In this study, we collected necropsy samples from various chicken breeds and tested for ARV by virus isolation, RT-PCR assay and sequence analysis. ARVs were isolated from birds showing runting-stunting syndrome, uneven growth, lameness or increased mortality, with relative detection rates of 38%, 35%, 6% and 25%, respectively. Partial ?C gene sequences were determined for nearly 90% of ARV isolates. The isolates could be classified into one of the major genetic clusters. Interestingly, cluster 2 and cluster 5 were isolated from vaccinated broiler breeders, while clusters 1 to 4 were isolated from unvaccinated broilers. The isolates shared less than 75% amino acid identities with the vaccine strains (range, 44.3?74.6%). This study reaffirms the global distribution of the major genetic clusters of ARVs in chicken. The diversity of ARV strains isolated from unvaccinated broilers was greater than those detected from vaccinated animals, however, the relative importance of passive and active immunity on the selection of novel strains in different chicken breeds needs to be better understood.
Tárgyszavak:Természettudományok Biológiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Animals. - 13 : 13 (2023), p. 1-13. -
További szerzők:Varga-Kugler Renáta Ihász Katalin Kaszab Eszter (1989-) (biológus) Domán Marianna (1987-) (biológus) Farkas Szilvia Bányai Krisztián
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

4.

001-es BibID:BIBFORM118255
035-os BibID:(cikkazonosító)1327725 (Scopus)85182813583
Első szerző:Jakab Szilvia
Cím:Genome stability assessment of PRRS vaccine strain with new ARTIC-style sequencing protocol / Szilvia Jakab, Ádám Bálint, Karolina Cseri, Krisztina Bali, Eszter Kaszab, Marianna Domán, Máté Halas, Krisztina Szarka, Krisztián Bányai
Dátum:2024
ISSN:2297-1769
Megjegyzések:A tiling amplicon sequencing protocol was developed to analyse the genome sequence stability of the modified live PRRSV vaccine strain, Porcilis MLV. The backbone of the ARTIC-style protocol was formed by 34 individual primer pairs, which were divided into two primer pools. Primer pairs were designed to amplify 532 to 588 bp fragments of the corresponding genomic region. The amplicons are suitable for sequencing on Illumina DNA sequencers with available 600-cycle sequencing kits. The concentration of primer pairs in the pools was optimized to obtain a balanced sequencing depth along the genome. Deep sequencing data of three vaccine batches were also analysed. All three vaccine batches were very similar to each other, although they also showed single nucleotide variations (SNVs) affecting less than 1 % of the genome. In the three vaccine strains, 113 to 122 SNV sites were identified; at these sites, the minority variants represented a frequency range of 1 to 48.7 percent. Additionally, the strains within the batches contained well-known length polymorphisms; the genomes of these minority deletion mutants were 135 to 222 bp shorter than the variant with the complete genome. Our results show the usefulness of ARTIC-style protocols in the evaluation of the genomic stability of PRRS MLV strains.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
deep sequencing
genetic variability
Porcilis MLV
porcine reproductive and respiratory syndrome virus
single nucleotide variation
tiling amplicon sequencing
Megjelenés:Frontiers in Veterinary Science. - 10 (2024), p. 1-8. -
További szerzők:Bálint Ádám Cseri Karolina (1985-) (molekuláris biológus) Bali Krisztina Kaszab Eszter (1989-) (biológus) Domán Marianna (1987-) (biológus) Halas Máté Szarka Krisztina (1971-) (molekuláris biológus, mikrobiológus) Bányai Krisztián
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

5.

001-es BibID:BIBFORM118358
035-os BibID:(Scopus)85183167838
Első szerző:Kaszab Eszter (biológus)
Cím:Metagenomic Identification of Novel Eukaryotic Viruses with Small DNA Genomes in Pheasants / Eszter Kaszab, Krisztina Bali, Szilvia Marton, Krisztina Ursu, Szilvia L. Farkas, Enikő Fehér, Marianna Domán, Vito Martella, Krisztián Bányai
Dátum:2024
ISSN:2076-2615
Megjegyzések:A panel of intestinal samples collected from common pheasants (Phasianus colchicus) between 2008 and 2017 was used for metagenomic investigation using an unbiased enrichment protocol and different bioinformatic pipelines. The number of sequence reads in the metagenomic analysis ranged from 1,419,265 to 17,507,704 with a viral sequence read rate ranging from 0.01% to 59%. When considering the sequence reads of eukaryotic viruses, RNA and DNA viruses were identified in the samples, including but not limited to coronaviruses, reoviruses, parvoviruses, and CRESS DNA viruses (i.e., circular Rep-encoding single-stranded DNA viruses). Partial or nearly complete genome sequences were reconstructed of at least three different parvoviruses (dependoparvovirus, aveparvovirus and chaphamaparvovirus), as well as gyroviruses and diverse CRESS DNA viruses. Generating information of virus diversity will serve as a basis for developing specific diagnostic tools and for structured epidemiological investigations, useful to assess the impact of these novel viruses on animal health. ? 2024 by the authors.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
genome assembly
phylogenetic analysis
virome
Megjelenés:Animals. - 14 : 2 (2024), p. 237, p. 1-13. -
További szerzők:Bali Krisztina Marton Szilvia Ursu Krisztina Farkas Szilvia L. Fehér Enikő (1981-) (molekuláris biológus, mikrobiológus) Domán Marianna (1987-) (biológus) Martella, Vito Bányai Krisztián
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1 
Corvina könyvtári katalógus v8.2.27 © 2023 Monguz kft. Minden jog fenntartva.