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001-es BibID:	BIBFORM104993
Első szerző:	Boldogh Bence Zoltán (Orvos)
Cím:	Hysteroscopic polypectomy in an outpatient setting / Bence Zoltán Boldogh, Luca Lukács, Márton György Lipták, Rudolf Lampé, Tünde Herman, Péter Török
Dátum:	2022
Megjegyzések:	Background Endometrial polyps are the most frequently observed benign lesions inside the uterine cavity. The incidence of them is reported about 20 % to 30 % in the female population. Endometrial polyps can be single or multiple, their size varies from a few millimetres to several centimetres. They can be totally asymptomatic or can cause abnormal uterine bleeding and/or infertility. They can be diagnosed by transvaginal ultrasonography, saline infusion ultrasonography, or by direct hysteroscopic visualization, but only the last can offer histological confirmation and proper treatment. Polyps can be removed by blind Dilatation and Curettage (D&C), or by hysteroscopy with direct visualization. Due to the miniaturization of the hysteroscopic devices, polypectomy can be made in an outpatient setting without general anaesthesia and hospitalization. The office-hysteroscopic removal of the polyp can be done with many operative techniques for example: with miniaturized instruments (grasping forceps, scissors), with mini-resectoscope, with tissue removal device (TRD), or with laser. Methods We retrospectively analysed the data of 125 patients, who underwent hysteroscopic polypectomy without general anaesthesia, in an outpatient office, between November 2016 to January 2022. Results The mean age was 41.46 ? 10.50 years, and the mean Body Mass Index (BMI) was 25.22 ? 5.87. The indications for performing office-hysteroscopy were the following: 79 (63.20%) abnormal sonographic findings, 27 (21.60%) infertility, and 19 (15.20%) abnormal uterine bleeding. Out of the 125 polypectomies, 74 (59.20%) were done with mechanical instruments (grasping forceps, scissors), 50 (40.00%) with mini-resectoscope, and 1 (0.80%) with laser. Conclusions Our data show that the toolkit of office-hysteroscopy is appropriate for the treatment of endometrial polyps furthermore, the polypectomy can be performed in an outpatient, cost-effective way without general anaesthesia and hospitalization.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk
Megjelenés:	Facts, views & vision in ObGyn. - 14 : 3 (2022), p. P257. -
További szerzők:	Lukács Luca (1995-) (hallgató) Lipták Márton György (1988-) (Orvos) Lampé Rudolf (1983-) (szülész-nőgyógyász) Herman Tünde (1979-) (orvos) Török Péter (1975-) (szülész-nőgyógyász)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM104438
Első szerző:	Lipták Márton György (Orvos)
Cím:	Resection of fibroids in outpatient setting / Lipták Márton, Boldogh Bence, Lukács Luca, Herman Tünde, Lampé Rudolf, Török Péter
Dátum:	2022
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk
Megjelenés:	Facts, views & vision in ObGyn. - 14 : 3 (2022), p. P134. -
További szerzők:	Boldogh Bence Zoltán (1995-) (Orvos) Lukács Luca (1995-) (hallgató) Herman Tünde (1979-) (orvos) Lampé Rudolf (1983-) (szülész-nőgyógyász) Török Péter (1975-) (szülész-nőgyógyász)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM104992
Első szerző:	Lukács Luca (hallgató)
Cím:	Out-patient selective tubal test with concomitant evaluation of the uterine cavity / Luca Lukács, Judit Lőrincz, Bence Boldogh, Márton György Lipták, Tünde Herman, Péter Török
Dátum:	2022
Megjegyzések:	Background Infertility is a common problem of couples with reproductive age. Tubal abnormality is an important cause of infertility, accounting for 25%?35% of female infertility. Tubal patency testing is important during infertility work-up before any assisted reproductive technique is performed. The relevance of diagnostic hysteroscopy, especially when performed in an outpatient "office" setting, in the evaluation process of infertility has increased in the last few years. During diagnostic hysteroscopy any morphological change of the uterine cavity or endometrium can be detected, not to mention the possibility for the tubal patency test. Our aim was to investigate the results of women who underwent selective pertubation with office hysteroscopy. Methods A total of 212 women were included in this retrospective study, who chose diagnostic office hysteroscopy during their infertility work-up. In each case before and after the procedure 3D ultrasound was used for evaluation of the uterine cavity. The selective pertubation with office hysteroscopy was performed in an outpatient setting, without general anaesthesia. Results Primary infertility (in 75 %), secondary infertility (in 22,17 %), repeated abortions (in 1,89 %), positive ultrasound results (in 0,94 % of the cases) made the indication for office hysteroscopy. The mean age of the patients was 33.1 ? 4.77. During the evaluation of uterine cavity 13 cases required polypectomy as well and 1 patient needed uterine myomectomy. Endometrial visualisation of 39 cases indicated biopsy as well during the evaluation with office hysteroscopy, this way 8 chronic endometritis were detected. Regarding the selective pertubation test, we detected positivity (tubal abnormality) in 61,32 % of the study, among them we explored unilateral occlusion in 43,08 % of the cases and bilateral occlusion in 56,92 % of the patients. No complications occurred during the 212 diagnostic office hysteroscopies. Conclusions Our results suggest this novel method, selective pertubation with office hysteroscopy, which is an effective, accurate, minimally invasive method to investigate tubal patency, in outpatient circumstances in order to choose proper assisted reproductive techniques. This way the complications of general anaesthesia or radiation (HSG) can be avoided. Moreover, with the examination of the uterine cavity, other factors, such as polyps, micropolyps, fibroids, chronic endometritis can be detected and treated so fertility can be improve as well.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk
Megjelenés:	Facts, views & vision in ObGyn. - 14 : 3 (2022), p. P124. -
További szerzők:	Lőrincz Judit (1988-) (általános orvos) Boldogh Bence Zoltán (1995-) (Orvos) Lipták Márton György (1988-) (Orvos) Herman Tünde (1979-) (orvos) Török Péter (1975-) (szülész-nőgyógyász)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM124149
035-os BibID:	(Scopus)85205047254 (WoS)001326252500001
Első szerző:	Orosz Mónika (Szülész-nőgyógyász)
Cím:	Endocrine Characteristics and Obstetric Outcomes of PCOS Patients with Successful IVF and Non-IVF Pregnancies / Orosz Mónika, Borics Fanni, Rátonyi Dávid, Krasznai Zoárd Tibor, Vida Beáta, Herman Tünde, Csehely Szilvia, Jakab Attila, Lukács Luca, Lampé Rudolf, Deli Tamás
Dátum:	2024
ISSN:	2077-0383
Megjegyzések:	Background/Objective: Infertility affects an estimated 40?50% of women with polycystic ovary syndrome (PCOS), the leading cause of anovulatory infertility, but only a small proportion of the patients require in vitro fertilization (IVF) therapy. Both PCOS and IVF are associated with an increased risk of obstetric complications. To compare preconception endocrine profiles and symptoms, as well as obstetric outcomes of PCOS patients who achieved successful pregnancies with and without IVF treatment. Methods: A single-center retrospective cohort study was conducted. Data spanning from 2012 to 2019 were compiled from patients with PCOS who visited the Gynecologic Endocrinology Unit and the Infertility Unit at the Department of Obstetrics and Gynecology, University of Debrecen. Patients diagnosed with PCOS who had had at least one successful delivery beyond the 23rd gestational week at the department were eligible for inclusion in the study. Results: Fifteen percent of the 206 pregnancies leading to successful deliveries of 232 newborns in our cohort conceived with IVF. A one year increase in the maternal age increased the odds of being in the IVF group by 22% (OR: 1.222, 95% confidence interval, CI: 1.11?1.35, p < 0.001). Baseline DHEAS and androstenedione levels were significantly lower in the IVF group as compared to the non-IVF group: 1 ?mol/L increase in the DHEAS level decreased the odds of being in the IVF group by 18% (OR: 0.82, 95% CI: 0.66?1.01, p = 0.06), and 1 ?g/L increase in the serum androstenedione concentration decreased the same odds by 42% (OR: 0.58, 95% CI: 0.33?1.02, p = 0.056). DHEAS levels <6.5 ?mol/L had an OR 3.86 (95% CI 1.10?13.50, p = 0.04) and LH/FSH ratio <1.3 had an OR 3.58 (95% CI 1.18?10.81, p = 0.03) for being in the IVF group. The birth weight (3069 ? 683 g vs. 3362 ? 638 g, p = 0.02) and the gestational age (37.23 ? 2.55 vs. 38.54 ? 2.28 weeks, p = 0.004) were significantly lower in the IVF group, but in the singleton subgroups, no significant differences could be found. Birth weight percentiles showed no significant difference in either subgroup. In the IVF group, both preterm delivery (29% vs. 8.3%, OR 4.53, 95% CI 1.75?11.70, p = 0.002; singleton subgroup: 17.4% vs. 6.3%, OR 3.12, 95% CI 0.89?10.92, p = 0.07) and cesarean section (71% vs. 43.2%, OR 3.22, 95% CI 1.40?7.40, p = 0.006; singleton subgroup: 65.2% vs. 42.4%, OR 2.55, 95% CI 1.02?6.35, p = 0.04) were more frequent than in the non-IVF group. Gestational diabetes and preeclampsia were not significantly different in the IVF and non-IVF groups. Conclusions: In PCOS patients with successful pregnancies, those who conceive with IVF seem to be different in their baseline hormone levels and symptoms from the non-IVF group. Adverse obstetric outcomes are more common in the IVF group, and some of these differences persist when adjusting for singleton pregnancies and maternal age, too.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk polycystic ovary syndrome pregnancy complications in vitro fertilization pre-pregnancy hormone levels obstetric outcomes androgen levels
Megjelenés:	Journal of Clinical Medicine. - 13 : 18 (2024), p. 1-13. -
További szerzők:	Borics Fanni (1995-) (orvos) Rátonyi Dávid (1996-) (Szülész-nőgyógyász) Krasznai Zoárd Tibor (1973-) (szülész-nőgyógyász, gyermeknőgyógyász) Vida Beáta (1994-) (szülészet-nőgyógyászat) Herman Tünde (1979-) (orvos) Csehely Szilvia (1990-) (szülész-nőgyógyász szakorvos) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Lukács Luca (1995-) (hallgató) Lampé Rudolf (1983-) (szülész-nőgyógyász) Deli Tamás (1979-) (szülész-nőgyógyász, endokrinológus szakorvos)
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