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001-es BibID:	BIBFORM124286
035-os BibID:	(scopus)85206560921 (wos)001333714900001
Első szerző:	Nurcholis, Waras
Cím:	Comparative Analysis of Volatile Compounds and Biochemical Activity of Curcuma xanthorrhiza Roxb. Essential Oil Extracted from Distinct Shaded Plants / Nurcholis Waras, Rahmadansah Rahmadansah, Astuti Puji, Priosoeryanto Bambang Pontjo, Arianti Rini, Kristóf Endre
Dátum:	2024
ISSN:	2223-7747
Megjegyzések:	The application of shade during plants' growth significantly alters the biochemical compounds of the essential oil (EO). We aimed to analyze the effect of shade on the volatile compounds and biochemical activities of EO extracted from Curcuma xanthorrhiza Roxb. (C. xanthorrhiza) plants. Four shading conditions were applied: no shading (S0), 25% (S25), 50% (S50), and 75% shade (S75). The volatile compounds of EO extracted from each shaded plant were analyzed by gas chromatography?mass spectrometry. The antioxidant, antibacterial, and antiproliferative activities of EO were also investigated. We found that shade application significantly reduced the C. xanthorrhiza EO yield but increased its aroma and bioactive compound concentration. ?-curcumene, xanthorrhizol, ?-cedrene, epicurzerenone, and germacrone were found in EO extracted from all conditions. However, ?-bisabolol, curzerene, curcuphenol, and ?-himachalene were only detected in the EO of S75 plants. The EO of the shaded plants also showed higher antioxidant activity as compared to unshaded ones. In addition, the EO extracted from S75 exerted higher antiproliferative activity on HeLa cells as compared to S0. The EO extracted from S0 and S25 showed higher antibacterial activity against Gram-positive bacteria than kanamycin. Our results suggest that shade applications alter the composition of the extractable volatile compounds in C. xanthorrhiza, which may result in beneficial changes in the biochemical activity of the EO.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Curcuma xanthorrhiza Roxb. essential oil antioxidant antibacterial anticancer
Megjelenés:	Plants-Basel. - 13 : 19 (2024), p. 1-17. -
További szerzők:	Rahmadansah, Rahmadansah Astuti, Puji Priosoeryanto, Bambang Pontjo Arianti, Rini (1991-) (biokémikus) Kristóf Endre (1987-) (általános orvos)
Pályázati támogatás:	PD146202 OTKA FK145866 OTKA
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM103477
035-os BibID:	(WoS)000851847700001 (Scopus)85137797604
Első szerző:	Nurcholis, Waras
Cím:	Effects of Methods and Durations of Extraction on Total Flavonoid and Phenolic Contents and Antioxidant Activity of Java Cardamom (Amomum compactum Soland Ex Maton) Fruit / Nurcholis Waras, Alfadzrin Rahma, Izzati Nurul, Arianti Rini, Vinnai Boglárka Ágnes, Sabri Fadillah, Kristóf Endre, Artika I. Made
Dátum:	2022
ISSN:	2223-7747
Megjegyzések:	Free radicals contribute to the pathophysiology of degenerative diseases which increase mortality globally, including mortality in Indonesia. Amomum compactum Soland. Ex Maton fruit from the Zingiberaceae family, also known as Java cardamom, contains secondary metabolites that have high antioxidant activities. The antioxidant activity of the methanol extract of Java cardamom fruit correlates with its flavonoid and phenolic compound contents, which can be affected by different methods and durations of extraction. This study aimed to measure and compare the effects of extraction methods and durations on total flavonoid and phenolic contents (TFCs and TPCs) and subsequent antioxidant activities by the 2,2·-diphenyl-1-picrylhydrazyl (DPPH) radical, ferric reducing antioxidant power (FRAP), 2,2·-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS), and cupric ion reducing antioxidant capacity (CUPRAC) assays. Methanol extracts of Java cardamom were produced by continuous shaking (CSE), microwave-assisted (MAE), or ultrasonic-assisted extractions (UAE) for three different durations. CSE for 360 min resulted in the highest TFCs (3.202 mg Quercetin Equivalent/g dry weight), while the highest TPCs (1.263 mg Gallic Acid Equivalent/g dry weight) were obtained by MAE for 3 min. Out of the investigated methods, MAE for 3 min resulted in the highest antioxidant activity results for the extracts. We conclude that the polyphenolic antioxidant yield of Java cardamom depends on two parameters: the method and the duration of extraction.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Plants-Basel. - 11 : 17 (2022), p. 1-13. -
További szerzők:	Alfadzrin, Rahma Izzati, Nurul Arianti, Rini (1991-) (biokémikus) Vinnai Boglárka Ágnes (1996-) (molekuláris biológus) Sabri, Fadillah Kristóf Endre (1987-) (általános orvos) Artika, I. Made
Pályázati támogatás:	FK131424 OTKA ÚNKP-21-3-I-DE-79 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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