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001-es BibID:BIBFORM091399
035-os BibID:(Scopus)85098571249 (cikkazonosító)9417 (WOS)000603017600001
Első szerző:Ádám Balázs (megelőző orvostan és népegészségtan szakorvos)
Cím:Use of Genomic Information in Health Impact Assessment is Yet to Come : a Systematic Review / Ádám Balázs, Lovas Szabolcs, Ádány Róza
Dátum:2020
ISSN:1661-7827 1660-4601
Megjegyzések:Information generated by genetic epidemiology and genomics studies has been accumulating at fast pace, and this knowledge opens new vistas in public health, allowing for the understanding of gene?environment interactions. However, the translation of genome-based knowledge and technologies to the practice of healthcare, and especially of public health, is challenging. Because health impact assessment (HIA) proved to be an effective tool to assist consideration of health issues is sectoral policymaking, this study aimed at exploring its role in the translational process by a systematic literature review on the use of genetic information provided by genetic epidemiology and genomics studies in HIA. PubMed, Scopus, and Web of Science electronic databases were searched and the findings systematically reviewed and reported by the PRISMA guidelines. The review found eight studies that met the inclusion criteria, most of them theoretically discussing the use of HIA for introducing genome-based technologies in healthcare practice, and only two articles considered, in short, the possibility for a generic application of genomic information in HIA. The findings indicate that HIA should be more extensively utilized in the translation of genome-based knowledge to public health practice, and the use of genomic information should be facilitated in the HIA process
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
genetic epidemiology
genomics
translation
health impact assessment
public health
public health genomics
Megjelenés:International Journal of Environmental Research and Public Health. - 17 : 24 (2020), p. 1-13. -
További szerzők:Lovas Szabolcs (1989-) (tudományos segédmunkatárs) Ádány Róza (1952-) (megelőző orvostan és népegészségtan szakorvos)
Pályázati támogatás:GINOP-2.3.2-15-2016-00005
GINOP
TK2016-78
OTKA
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2.

001-es BibID:BIBFORM100148
Első szerző:Lovas Szabolcs (tudományos segédmunkatárs)
Cím:Chemical pollutants in closed environments of transportation and storage of non-dangerous goods - Insufficient legislation, low awareness, and poor practice in Hungary / Szabolcs Lovas, Orsolya Varga, Tom Loney, Balázs Ádám
Dátum:2022
ISSN:0960-3123
Megjegyzések:Several chemical pollutants can accumulate within the closed environments of transportation and storage. Pollutants are mainly residues of pesticides, volatile organic compounds and components of diesel exhaust. The study objectives were to (i) review the regulations relevant to occupational chemical exposures in closed environments of inland transportation and storage; and (ii) explore the practice of preventing these exposures. A systematic search and content analysis of international and Hungarian nation legal documents were carried out. In addition, semi-structured interviews with occupational health and safety (OHS) professionals and warehouse managers were conducted. Analysis of legal documents highlighted the lack of explicit regulations on the investigated problem. The 21 interviews revealed that the participants had limited knowledge about the pollutants; they deemed chemical exposure rare and related health effects negligible. The revealed limitations indicate that this field should be more specifically regulated and OHS professionals should be better informed about these workplace hazards.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
occupational chemical exposure
pesticide residues
closed environments of transportation and storage
Megjelenés:International Journal Of Environmental Health Research. - 6 (2022), p. 1-18. -
További szerzők:Varga Orsolya (1987-) (radiográfus (BSc) Loney, Tom Ádám Balázs (1973-) (megelőző orvostan és népegészségtan szakorvos)
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3.

001-es BibID:BIBFORM095550
035-os BibID:(cikkazonosító)7052 (Scopus)85108952405 (WOS)000671271500001
Első szerző:Lovas Szabolcs (tudományos segédmunkatárs)
Cím:Presumed Exposure to Chemical Pollutants and Experienced Health Impacts among Warehouse Workers at Logistics Companies : a Cross-Sectional Survey / Szabolcs Lovas, Károly Nagy, János Sándor, Balázs Ádám
Dátum:2021
ISSN:1661-7827 1660-4601
Megjegyzések:During intercontinental shipping, freight containers and other closed transport devices are applied. These closed spaces can be polluted with various harmful chemicals that may accumulate in poorly ventilated environments. The major pollutants are residues of pesticides used for fumigation as well as volatile organic compounds (VOCs) released from the goods. While handling cargos at logistics companies, workers can be exposed to these pollutants, frequently without adequate occupational health and safety precautions. A cross-sectional questionnaire survey was conducted among potentially exposed warehouse workers and office workers as controls at Hungarian logistics companies (1) to investigate the health effects of chemical pollutants occurring in closed spaces of transportation and storage and (2) to collect information about the knowledge of and attitude toward workplace chemical exposures as well as the occupational health and safety precautions applied. Pre-existing medical conditions did not show any significant difference between the working groups. Numbness or heaviness in the arms and legs (AOR = 3.99; 95% CI = 1.72?9.26) and dry cough (AOR = 2.32; 95% CI = 1.09?4.93) were significantly associated with working in closed environments of transportation and storage, while forgetfulness (AOR = 0.40; 95% CI = 0.18?0.87), sleep disturbances (AOR = 0.36; 95% CI = 0.17?0.78), and tiredness after waking up (AOR = 0.40; 95% CI = 0.20?0.79) were significantly associated with employment in office. Warehouse workers who completed specific workplace health and safety training had more detailed knowledge related to this workplace chemical issue (AOR = 8.18; 95% CI = 3.47?19.27), and they were significantly more likely to use certain preventive measures. Warehouse workers involved in handling cargos at logistics companies may be exposed to different chemical pollutants, and the related health risks remain unknown if the presence of these chemicals is not recognized. Applied occupational health and safety measures at logistics companies are not adequate enough to manage this chemical safety issue, which warrants awareness raising and the introduction of effective preventive strategies to protect workers' health at logistics companies.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
chemical pollutant
freight container
logistics
pesticide
volatile organic compound
warehouse
Megjelenés:International Journal of Environmental Research and Public Health. - 18 : 13 (2021), p. 1-14. -
További szerzők:Nagy Károly (1986-) (népegészségügyi felügyelő) Sándor János (1966-) (orvos-epidemiológus) Ádám Balázs (1973-) (megelőző orvostan és népegészségtan szakorvos)
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4.

001-es BibID:BIBFORM085694
035-os BibID:(cikkazonosító)108926
Első szerző:Nagy Károly (népegészségügyi felügyelő)
Cím:Systematic review of comparative studies assessing the toxicity of pesticide active ingredients and their product formulations / Nagy Károly, Duca Radu Corneliu, Lovas Szabolcs, Creta Matteo, Scheepers Paul T. J., Godderis Lode, Ádám Balázs
Dátum:2020
ISSN:0013-9351
Megjegyzések:Humans are exposed to complex chemical mixtures, such as pesticides. Although the need for the assessment of health and environmental hazards deriving from the interactions between various substances found in commercial pesticide formulations is becoming increasingly recognized, the approval of pesticide products is still mostly limited to determining the toxicity of the individual ingredients ignoring the possible combined effects in mixtures. The objective of this study was to systematically review the literature of in vitro and in vivo studies that simultaneously examine the toxicity of pesticide product formulations and their declared active ingredients to compare their toxicity to human health and to the environment. Two electronic databases were searched for studies that assessed the health effects of active pesticide ingredients and their product formulations. The literature search was performed with a combination of the following terms: "pesticide", "formulation", "commercial product", "commercial pesticide" and "health". After screening by predefined inclusion and exclusion criteria, quality and reliability assessment of eligible publications was conducted by use of the ToxRTool. Two investigators independently screened the identified publications and extracted results from eligible studies. Our search yielded 36 toxicity studies; 23 studies investigated herbicides, 15 examined insecticides and 4 focused on fungicides. Twenty-four studies reported increased toxicity of the product formulations versus their active ingredients, which, in most cases, were attributed to the presence of adjuvants in the formulations. A significant number (n = 10) of studies focused on the comparative testing of glyphosate and glyphosate-based herbicides, and six of them concluded that Roundup, the dominant product formulation of glyphosate, is more toxic than the active ingredient alone. We identified only 8 studies demonstrating reduced toxicity of product formulations in relation to the active ingredient that might be due to a potential antagonistic effect between the constituents. The results of this review demonstrate the inadequacy of current EU testing requirements for assessing the health hazards of pesticide product formulations based mainly on the evaluation of the individual ingredients and of at least one representative use and formulation. Ignoring the possible risks deriving from the interaction between the active and other ingredients of various commercial pesticide product formulations might result in the misinterpretation of its toxicological profile. At EU level efforts are currently made to address this issue. In this context, we recommend that all product formulations should be fully assessed during the authorization process.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Environmental Research. - 181 (2020), p. 1-19. -
További szerzők:Duca, Radu Corneliu Lovas Szabolcs (1989-) (tudományos segédmunkatárs) Creta, Matteo Scheepers, Paul T. J. Godderis, Lode Ádám Balázs (1973-) (megelőző orvostan és népegészségtan szakorvos)
Pályázati támogatás:EFOP-3.6.1-16-2016-00022
EFOP
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