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1.
001-es BibID:
BIBFORM106134
035-os BibID:
(WOS)000904416000001 (Scopus)85144635665
Első szerző:
Astuti, Putri Kusuma (állattenyésztési genetikus)
Cím:
Validation of SNP markers for thermotolerance adaptation in Ovis aries adapted to different climatic regions using KASP-PCR technique / Putri Kusuma Astuti, Daniela Elena Ilie, Dinu Gavojdian, George Wanjala, Bouabid Badaoui, Husein Ohran, Eva Pasic-Juhas, Zoltán Bagi, András Jávor, Szilvia Kusza
Dátum:
2022
ISSN:
2045-2322
Megjegyzések:
A study on 51 SNPs belonging to 29 genes related to heat stress was carried out in 720 sheep from 17 different breeds adapted to different climates from Hungary, Bosnia and Herzegovina, Morocco and Romania, using Kompetitive Allele?Specific Polymerase Chain Reaction. Genotype frequency and the Hardy?Weinberg equilibrium were calculated, followed by a clustering using the Principal Component Analysis. We analyzed the polymorphisms in the following genes analyzed: HSPA12A, HSP90AA1, IL33, DIO2, BTNL2, CSN2, ABCG1, CSN1S1, GHR, HSPA8, STAT3, and HCRT. We emphasized on HSPA12A and HSPA8 genes as they were successfully genotyped in all studied flocks in which genotype frequency patterns were identified. Contrary to previous findings, the A allele for HSPA8 SNP was not observed in the heat tolerant breeds, being found exclusively in cold-tolerant breeds. The principal component analysis could not clearly differentiate the breeds, while plot concentration was slightly varied among the three groups, with HSP90AA1 and IL33 SNPs' loading values significantly contributing to PC1 and PC2. We confirmed previous works that the HSPA12A, HSPA8, HSP90AA1 and IL33 SNPs are potential candidate markers for thermotolerance adaptation in sheep. This research contributes to the genetic variability of SNPs for thermotolerance adaptability in sheep.
Tárgyszavak:
Agrártudományok
Állattenyésztési tudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:
Scientific Reports. - 12 (2022), p. 1-9. -
További szerzők:
Ilie, Daniela Elena
Gavojdian, Dinu
Wanjala, George (1984-) (Animal scientist)
Badaoui, Bouabid (1979-) (animal genetics engineer)
Ohran, Husein
Pasic-Juhas, Eva
Bagi Zoltán (1987-) (természetvédelmi mérnök, állatgenetika)
Jávor András (1952-) (agrármérnök)
Kusza Szilvia (1979-) (agrármérnök)
Pályázati támogatás:
EFOP-3.6.2-16-2017-00001
EFOP
2021-1.2.4-TÉT-2021-00014
Egyéb
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
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Saját polcon:
2.
001-es BibID:
BIBFORM122766
035-os BibID:
(Scopus)85198652941
Első szerző:
Kichamu, Nelly (Animal scientist)
Cím:
Assessing the population structure and genetic variability of Kenyan native goats under extensive production system / Nelly Kichamu, George Wanjala, Ludovic Toma Cziszter, Péter Strausz, Putri Kusuma Astuti, Zoltán Bagi, Szilvia Kusza
Dátum:
2024
ISSN:
2045-2322
Megjegyzések:
Indigenous goats are important to many livelihoods. Despite this, they are subjected to indiscriminate crossbreeding. This afects their genetic variability which is needed to survive in current regime of climate change. The study assessed population structure and genetic diversity of Galla and Small East African goats (SEA) using pedigree information. A total of 7384 animals, 5222 of the Galla and 2162 of the SEA breeds, born between the years 1983 and 2022, were utilized. Individuals with known parents were defned as reference population. From the results, the maximum generation traced for Galla and SEA populations was 14.6 and 14.5, respectively. However, only 6 and 5 generations for Galla and SEA were complete. Pedigree completeness increased with the increasing number of generations. The average generation interval (GI) for Galla and SEA was 3.84 ± 0.04 and 4.4 ± 0.13 years. The average increase in the rate of inbreeding per generation for Galla and SEA was 0.04 and 0.05, with the efective ancestors and founders (fa/fe) ratio being same (1.00) for both breeds. Fifty percent (50%) of the genetic variability in the populations was contributed by 3 and 1 ancestor for Galla SEA, respectively. The efective population size (Ne) was 5.19 and 4.77 for Galla and SEA. Therefore, the current breeding programs should be changed to avoid future genetic bottlenecks in this population. These fndings ofer an opportunity to enhance the current genetic status and management of Kenyan native goats and other regions with similar production systems.
Tárgyszavak:
Agrártudományok
Állattenyésztési tudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:
Scientific Reports. - 14 : 1(2024), p. 1-11. -
További szerzők:
Wanjala, George (1984-) (Animal scientist)
Cziszter, Ludovic Toma
Strausz Péter
Astuti, Putri Kusuma (1994-) (állattenyésztési genetikus)
Bagi Zoltán (1987-) (természetvédelmi mérnök, állatgenetika)
Kusza Szilvia (1979-) (agrármérnök)
Internet cím:
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
3.
001-es BibID:
BIBFORM129638
035-os BibID:
(Scopus)105003158632 (WoS)001473869700019
Első szerző:
Wanjala, George (Animal scientist)
Cím:
Genetic diversity and adaptability of native sheep breeds from different climatic zones / George Wanjala, Zoltán Bagi, Dinu Gavojdian, Bouabid Badaoui, Putri Kusuma Astuti, Alexandru Mizeranschi, Elena Ilisiu, Husein Ohran, Eva Pasic Juhas, Dimitrios Loukovitis, Aldona Kawȩcka, Rūta Šveistienẻ, Zsolt Becskei, Péter Strausz, Nelly Kichamu, Szilvia Kusza
Dátum:
2025
ISSN:
2045-2322
Megjegyzések:
To better understand the genetic architecture and adaptability of native sheep, 22 breeds were genotyped using ovine50K SNP chips. Eleven additional populations from open-source repositories were included. Cross population Extended Haplotype Homozygosity (XP-EHH) and Relative Scaled Haplotype Homozygosity (Rsb) haplotype-based approaches were used to identify genetic variations influencing the adaptation of local sheep breeds to different climatic zones. The results indicate that all breeds exhibited high but declining genetic diversity levels, with a larger proportion of genetic variation explained by development history and refined by geographical origin, as shown by principal component analysis and Neighbor Net graphs. Admixture analysis revealed high admixture levels in European and North African breeds. Using XP-EHH and Rsb methods, 371 genes were putatively under selection, with only nine common among all population pairs, highlighting unique adaptability. Most identified genes, including Interleukin (IL) and cluster differentiation (CD) gene families underlie immune responses, emphasizing their role in resilience to climate change effects. These findings support that indigenous sheep breeds have retained significant genetic diversity, but improper genetic management may threaten it. Additionally, the research emphasizes that indigenous sheep breeds' unique adaptability to specific climatic zones makes them valuable genetic assets for developing climate-resilient breeds.
Tárgyszavak:
Agrártudományok
Állattenyésztési tudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:
Scientific Reports. - 15 : 14143 (2025), p. 1-13. -
További szerzők:
Bagi Zoltán (1987-) (természetvédelmi mérnök, állatgenetika)
Gavojdian, Dinu
Badaoui, Bouabid (1979-) (animal genetics engineer)
Astuti, Putri Kusuma (1994-) (állattenyésztési genetikus)
Mizeranschi, Alexandru Eugeniu
Ilisiu, Elena
Ohran, Husein
Pasic Juhas, Eva
Loukovitis, Dimitrios
Kawęcka, Aldona
Šveistienẻ, Rūta
Becskei Zsolt
Strausz Péter
Kichamu, Nelly (1978-) (Animal scientist)
Kusza Szilvia (1979-) (agrármérnök)
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
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