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001-es BibID:BIBFORM099403
Első szerző:Bálint István Bence
Cím:Is duodeno-jejunal bypass liner superior to pylorus preserving bariatric surgery in terms of complications and efficacy? / Istvan Bence Bálint, Ferenc Csaszar, Krisztián Somodi, László Ternyik, Adrienn Biro, Zsolt Kaposztas
Dátum:2021
ISSN:1435-2443
Megjegyzések:Purpose: Based on recent scientific evidence, bariatric surgery is more effective in the management of morbid obesity and related comorbidities than conservative therapy. Pylorus preserving surgical procedures (PPBS) such as laparoscopic single-anastomosis duodeno-jejunal or duodeno-ileal bypass with sleeve gastrectomy are modified duodenal switch (DS) surgical techniques. The duodeno-jejunal bypass liner (DJBL) is a novel surgical method in the inventory of metabolism focused manual interventions that excludes duodeno-jejunal mucosa from digestion, mimicking DS procedures without the risk of surgical intervention. The aim of this article is to summarize and compare differences between safety-related features and weight loss outcomes of DJBL and PPBS. Methods: A literature search was conducted in the PubMed database. Records of DJBL-related adverse events (AEs), occurrence of PPBS-related complications and reintervention rates were collected. Mean weight, mean body mass index (BMI), percent of excess of weight loss (EWL%), percent of total weight loss (TWL%) and BMI value alterations were recorded for weight loss outcomes. Results: A total of 11 publications on DJBL and 6 publications on PPBS were included, involving 800 and 1462 patients, respectively. The baseline characteristics of the patients were matched. Comparison of DJBL-related AEs and PPBS-related severe complications showed an almost equal risk (risk difference (RD): ?0.03 and confidence interval (CI): ?0.27 to 0.21), despite higher rates among patients having received endoscopic treatment. Overall AE and complication rates classified by Clavien-Dindo showed that PPBS was superior to DJBL due to an excess risk level of 25% (RD: 0.25, CI: 0.01?0.49). Reintervention rates were more favourable in the PPBS group, without significant differences in risk (RD: ?0.03, CI: ?0.27 to 0.20). However, PPBS seemed more efficient regarding weight loss outcomes at 1-year follow-up according to raw data, while meta-analysis did not reveal any significant difference (odds ratio (OR): 1.08, CI: 0.74?1.59 for BMI changes).
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Pylorus preserving
Bariatric surgery
Metabolic surgery
Single-anastomosis duodeno-jejunal bypass
Single-anastomosis duodeno-ileal bypass
Duodenal switch
Duodeno-jejunal bypass liner
EndoBarrier
Megjelenés:Langenbecks Archives Of Surgery. - 406 : 5 (2021), p. 1363-1377. -
További szerzők:Császár Ferenc Somodi Krisztián Ternyik László Biró Adrienn (1988-) (orvos) Káposztás Zsolt
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001-es BibID:BIBFORM099505
035-os BibID:(WoS)000729060700002 (Scopus)85122150737
Első szerző:Biró Adrienn (orvos)
Cím:Comparison of Resected Malignant Tumors of the Right- and Left-Sided Colon : Is There a Difference? / Biró Adrienn, Ternyik László, Somodi Krisztián, Dawson Anna, Csulak Eszter, Tóth Dezső, Moizs Mariann, Káposztás Zsolt
Dátum:2022
ISSN:0972-2068 0973-9793
Megjegyzések:Embryological, anatomical, and immunological differences between the right-sided and left-sided colons are well known, but the difference in oncological behavior of colon tumors has only recently become the main subject of studies. Published articles propose that there is a difference not only in symptoms, but also in survival. Our aim was to analyze the clinicopathological and oncological differences among our patients who had been operated for colon cancer in our department. We examined the historical data of our patients who underwent colon resection for malignancy between 1st of January 2016 and 31st of December 2018. Tumor markers, histological results, postoperative complications, and oncological therapies were investigated. The primary outcome was overall survival. We analyzed our patients' survival data with Kaplan?Meier log-rank test and Cox regression analysis. In our study, 267 patients were enrolled. One hundred thirty-three (49.8%) patients had right-sided colon cancer; 134 (50.2%) patients had left-sided colon cancer. Patients with right-sided colon cancer were significantly more likely to have mucinous adenocarcinoma (p=0.037). No significant differences were revealed in overall survival between right-sided colon cancer and left-sided colon cancer patients (p=0.381). Additional subgroup analysis showed that there were no significant differences in overall survival for laterality neither in the metastatic group (p=0.824) nor in the non-metastatic group (p=0.345). Based on the conficting previous study results, our findings repeatedly highlight that the relationship between tumor location in the colon and overall survival is not straightforward.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Colon cancer
Tumor
Sidedness
Laterality
Survival
Megjelenés:Indian Journal of Surgery. - 84 : 5 (2022), p. 971-978. -
További szerzők:Ternyik László Somodi Krisztián Dawson Anna Csulak Eszter Tóth Dezső (1972-) (sebész, onkológus) Moizs Marianna (1964-) (orvos) Káposztás Zsolt
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DOI
Intézményi repozitóriumban (DEA) tárolt változat
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