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001-es BibID:	BIBFORM038477
Első szerző:	Módis László (szemész szakorvos, kontaktológus)
Cím:	Distribution of antioxidant enzymes in the normal aged human conjunctiva : an immunocytochemical study / Módis László, Marshall George E., Lee William R.
Dátum:	1998
ISSN:	0721-832X
Megjegyzések:	Background: The pur- pose of the study was to map the precise location of four antioxidant enzymes in the normal human con- junctiva. Methods: Conjunctival tissue (seventeen specimens) from seven patients was processed for light microscopy and immunogold electron microscopy. Antibodies were used to label glutathione peroxidase, gluta- thione S-transferase (acidic and neu- tral forms) and copper/zinc superox- ide dismutase. Results: All layers of the epithelium exhibited labelling for all four enzymes, although there were differences in labelling intensi- ties and distribution between the en- zymes. Wing cells showed more in- tense labelling for glutathione perox- idase, glutathione S-transferase (neu- tral form) and copper/zinc superoxide dismutase than did basal and super- ficial cells. The strongest immunore- activity was detected for glutathione S-transferase (acidic) and was equal- ly strong in the superficial and wing cells. Wing cells demonstrated more immunoreactivity in the cell nuclei with antibodies against all four en- zymes. A high degree of labelling was also observed in the microplicae and actin cortex of the superficial cells. Leukocytes, fibroblasts, endo- thelial cells and erythrocytes within the stroma exhibited minimal label- ling. Conclusion: The subtle changes in distribution of antioxidant enzymes in the normal human con- junctival epithelium most probably reflect exposure to free radicals in the tear film and are based on the dif- ferent proliferative and functional activities of each of the anatomical layers.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Graefes Archive For Clinical And Experimental Ophthalmology. - 236 : 2 (1998), p. 86-90. -
További szerzők:	Marshall, George E. Lee, William R.
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM020309
Első szerző:	Módis László (szemész szakorvos, kontaktológus)
Cím:	Corneal transplantation in Hungary (1946-2009) / Módis L. Jr., Szalai E., Facskó A., Fodor M., Komár T., Berta A.
Dátum:	2011
ISSN:	1442-6404
Megjegyzések:	To identify changing trends in indications for corneal transplantation in Debrecen, Hungary over the past 64 years. DESIGN: Retrospective study, at the Department of Ophthalmology, University of Debrecen, Hungary. PARTICIPANTS: Four thousand seven hundred and seventy-eight patients who underwent keratoplasty. METHODS: The analysis was based on medical charts, surgical descriptions and eye bank records. MAIN OUTCOME MEASURES: Keratoplasty indications between January 1946 and December 2009. For an easier overview, the 64-year interval was divided into seven time periods (1946-1955, I; 1956-1965, II; 1966-1975, III; 1976-1985, IV; 1986-1995, V; 1996-2005, VI; 2006-2009, VII). RESULTS: Over the 64 years, clinical indications for keratoplasty were corneal scarring (24.9%), regraft (18.6%), keratoconus (18.6%), pseudophakic/aphakic corneal oedema (12%), stromal corneal dystrophies (6%), non-infectious keratitis (4.7%), chemical injuries (3.3%), corneal degenerations (3%), mechanical trauma (1.7%), infectious keratitis (1.4%), endothelial corneal dystrophies (1.3%) and others (4.5%). During periods I-IV, corneal scarring was the most common indication for corneal transplantation. In period V, corneal ectasia became the leading clinical indication. Regraft was the most frequent indication in period VI. In the most recent years, an emerging tendency in pseudophakic/aphakic corneal oedema as the indication for keratoplasty was observed. CONCLUSIONS: In Hungary, the number of grafts has increased greatly in the past 64 years, the transplantation rates are similar to those of industrial countries. Indications for corneal transplantation have changed considerably over the last half decade from corneal scarring to corneal ectasia, regraft and pseudophakic/aphakic corneal oedema.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Clinical And Experimental Ophthalmology. - 39 : 6 (2011), p. 520-525. -
További szerzők:	Szalai Eszter (1984-) (orvos) Facskó Andrea (1953-) (szemész) Fodor Mariann (1975-) (szemész) Komár Timea (1975-) (szemész) Berta András (1955-) (szemész, gyermekszemész)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM038396
Első szerző:	Németh Gábor (szemész)
Cím:	Comparison of intraocular lens power prediction using immersion ultrasound and optical biometry with and without formula optimization / Nemeth Gabor, Nagy Attila, Berta Andras, Modis Laszlo
Dátum:	2012
ISSN:	0721-832X
Megjegyzések:	Purpose Comparison of postoperative refraction results using ultrasound biometry with closed immersion shell and optical biometry. Patients and method Three hundred and sixty-four eyes of 306 patients (age: 70.6±12.8 years) underwent cataract surgery where intraocular lenses calculated by SRK/T formula were implanted. In 159 cases immersion ultrasonic biometry, in 205 eyes optical biometry was used. Differences between predicted and actual postoperative refractions were calculated both prior to and after optimization with the SRK/ T formula, after which we analysed the similar data in the case of Holladay, Haigis, and Hoffer-Q formulas. Mean absolute error (MAE) and the percentage rate of patients within ±0.5 and ±1.0 D difference in the predicted error were calculated with these four formulas. Results MAE was 0.5-0.7 D in cases of both methods with SRK/T, Holladay, and Hoffer-Q formula, but higher with Haigis formula. With no optimization, 60-65 % of the patients were under 0.5 D error in the immersion group (except for Haigis formula). Using the optical method, this value was slightly higher (62-67 %), however, in this case, Haigis formula also did not perform so well (45 %). Refraction results significantly improved with Holladay, Hoffer-Q, and Haigis formulas in both groups. The rate of patients under 0.5 D error increased to 65 % by the immersion technique, and up to 80 % by the optical one. Conclusions According to our results, optical biometry offers only slightly better outcomes compared to those of immersion shell with no optimized formulas. However, in case of new generation formulas with both methods, the optimization of IOL-constants give significantly better results.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban IOL-constants immersion biometry optical biometry optimization
Megjelenés:	Graefes Archive For Clinical And Experimental Ophthalmology. - 250 : 9 (2012), p. 1321-1325. -
További szerzők:	Nagy Attila (szemész) Berta András (1955-) (szemész, gyermekszemész) Módis László (1964-) (szemész szakorvos, kontaktológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM038410
Első szerző:	Sohajda Zoltán (szemész)
Cím:	Microcornea associated with myopia / Sohajda Zoltán, Holló Dóra, Berta András, Módis László
Dátum:	2006
ISSN:	0721-832X
Megjegyzések:	Background: The presentation of microcornea associated with axial myopia by means of modern examination techniques. Methods: Clinical investigations. Results: The horizontal diameter of the cornea was 8.00 mm on both sides. The average refractive power of the cornea was 39.27D/38.48D on the right/left sides by corneal topography. The central corneal thickness was 568 um/ 559 um on the right and left sides, respectively. The depth of the anterior chamber was 1.18 mm/1.14 mm and the origin of the irises was steep, as demonstrated by ultrasound biomicroscopy (UBM). The axial length was 26.42 mm/25.63 mm on the right/left sides. Endothelial morphology disclosed degeneration on both sides. Conclusions: The present case demonstrates that the clinical signs of microcornea are flat corneal surface, normal thickness, and degenerated endothelium. This disorder associated with axial myopia is an extre
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Microcornea Pachymetry Cornea topography Axial myopia
Megjelenés:	Graefes Archive For Clinical And Experimental Ophthalmology. - 244 : 9 (2006), p. 1211-1213. -
További szerzők:	Holló Dóra Berta András (1955-) (szemész, gyermekszemész) Módis László (1964-) (szemész szakorvos, kontaktológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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