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001-es BibID:BIBFORM115341
035-os BibID:(WoS)001123624500001 (Scopus)85179364233
Első szerző:Deibel, Elisabeth
Cím:Does the impact of COVID-19 on patients with systemic sclerosis change over time? / Deibel Elisabeth, Carreira Patricia E., Vonk Madelon, del Papa Nicoletta, Becvár Radim, Guillén-Del-Castillo Alfredo, Campochiaro Corrado, Poormoghim Hadi, Liem Sophie, Lazzaroni Maria-Grazia, Giollo Alessandro, Mekinian Arsene, de Vries-Bouwstra Jeska, De Santis Maria, Balbir-Gurman Alexandra, Mihai Carina, De Luca Giacomo, Moiseev Sergey, Zanatta Elisabetta, Foti Rosario, Rednic Simona, Denton Christopher, Cutolo Maurizio, Belloli Laura, Airo Paolo, Garzanova Liudmila, Moroncini Gianluca, Inanc Murat, Panopoulos Stylianos, Tandaipan Jose-Luis, Chatelus Emmanuel, Rosato Edoardo, Kuwana Masataka, Yavuz Sule, Alegre-Sancho Juan J., Smith Vanessa, Szűcs Gabriella, Henes Jörg, Rodríguez-Pintó Ignasi, Atzeni Fabiola, Spierings Julia, Truchetet Marie-Elise, Milchert Marcin, Brito de Araujo Daniel, Riemekasten Gabriela, Bernardino Vera, Martin Thierry, del Galdo Francesco, Vacca Alessandra, Mendoza Fabian, Midtvedt Øyvind, Murdaca Giuseppe, Santiago Tania, Codullo Veronica, Cacciapaglia Fabio, Walker Ulrich, Brunborg Cathrine, Tirelli Francesca, Allanore Yannick, Furst Daniel E., Matucci Marco, Gabrielli Armando, Distler Oliver, Hoffmann-Vold Anna-Maria
Dátum:2024
ISSN:2151-464X 2151-4658
Megjegyzések:Objective. The outcome of patients with COVID-19 improved over the pandemic, including patients with systemic rheumatic diseases. However, data on patients with systemic sclerosis (SSc) are lacking. This study aimed to assess the outcome of patients with both SSc and COVID-19 over several waves.Methods. Patients with both SSc and COVID-19 who were registered in the European Scleroderma Trials and Research group (EUSTAR) were collected between April 2020 and April 2021. Patients were assigned to waves 1, 2, or 3 depending on the date of their COVID-19 diagnosis. Primary endpoints were death, intensive care unit stay, or ventilatory support (severe outcome). Subgroup analyses of patients who were hospitalized or died were conducted. General and SSc-specific characteristics and treatment were compared over the waves. Descriptive statistics and multivariate logistic regression were applied.Results. A total of 333 patients were included; 57 patients (17%) had a severe outcome, and 30 patients (9%) died. Compared to wave 1, significantly fewer patients with SSc suffered from severe COVID-19 in waves 2 and 3 (28.2% vs 9.8% and 12.7%; P < 0.001), fewer patients required hospitalization (46.7% vs 19.6% and 25.5%; P < 0.001) or ventilatory support (24.0% vs 8.7% and 10.9%; P = 0.001), and fewer patients died (15.7% vs 5.0% and 7.5%; P = 0.011). Patients were significantly younger, more often men, had less frequent arterial hypertension, and less SSc cardiac involvement over waves 1 to 3. Patients received significantly less medium to high doses of corticosteroids as they did SSc treatment.Conclusion. The outcome of patients with both SSc and COVID-19 improved significantly over time because of intrinsic and extrinsic factors.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Arthritis Care And Research. - 76 : 1 (2024), p. 88-97. -
További szerzők:Carreira, Patricia E. Vonk, Madelon C. del Papa, Nicoletta Becvar, Radim Guillén-Del-Castillo, Alfredo Campochiaro, Corrado Poormoghim, Hadi Liem, Sophie Lazzaroni, Maria-Grazia Giollo, Alessandro Mekinian, Arsene de Vries-Bouwstra, Jeska De Santis, Maria Balbir Gurman, Alexandra Mihai, Carina De Luca, Giacomo Moiseev, Sergey Zanatta, Elisabetta Foti, Rosario Rednic, Simona Denton, Christopher Cutolo, Maurizio Belloli, Laura Airò, Paolo Garzanova, Liudmila Moroncini, Gianluca Inanc, M. Panopoulos, Stylianos Tandaipan, José-Luis Chatelus, Emmanuel Rosato, Edoardo Kuwana, Masataka Yavuz, Sule Alegre-Sancho, Juan Jose Smith, Vanessa Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Henes, Jörg Rodríguez-Pintó, Ignasi Atzeni, Fabiola Spierings, Julia Truchetet, Marie-Elise Milchert, Marcin Brito de Araujo, Daniel Riemekasten, Gabriela Bernardino, Vera Martin, Thierry del Galdo, Francesco Vacca, Alessandra Mendoza, Fabian A. Midtvedt, Øyvind Murdaca, Giuseppe Santiago, Tania Codullo, Veronica Cacciapaglia, Fabio Walker, Ulrich Brunborg, Cathrine Tirelli, Francesca Allanore, Yannick Furst, Daniel E. Matucci-Cerinic, Marco Gabrielli, Armando Distler, Oliver Hoffmann-Vold, Anna-Maria
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001-es BibID:BIBFORM078731
035-os BibID:(PMID)30967395 (WoS)000471138100030 (Scopus)85064192589
Első szerző:Elhai, Muriel
Cím:Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice : a prospective cohort study / Muriel Elhai, Marouane Boubaya, Oliver Distler, Vanessa Smith, Marco Matucci-Cerinic, Juan José Alegre Sancho, Marie-Elise Truchetet, Yolanda Braun-Moscovici, Florenzo Iannone, Pavel I. Novikov, Alain Lescoat, Elise Siegert, Ivan Castellví, Paolo Airó, Serena Vettori, Ellen De Langhe, Eric Hachulla, Anne Erler, Lidia Ananieva, Martin Krusche, F. J. López-Longo, Jörg H. W. Distler, Nicolas Hunzelmann, Anna-Maria Hoffmann-Vold, Valeria Riccieri, Vivien M. Hsu, Maria R. Pozzi, Codrina Ancuta, Edoardo Rosato, Carina Mihai, Masataka Kuwana, Lesley Ann Saketkoo, Carlo Chizzolini, Roger Hesselstrand, Susanne Ullman, Sule Yavuz, Simona Rednic, Cristian Caimmi, Coralie Bloch-Queyrat, Yannick Allanore, EUSTAR network
Dátum:2019
ISSN:0003-4967
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
lung fibrosis
rituximab
skin fibrosis
systemic sclerosis
Megjelenés:Annals Of The Rheumatic Diseases. - 78 : 7 (2019), p. 979-987. -
További szerzők:Boubaya, Marouane Distler, Oliver Smith, Vanessa Matucci-Cerinic, Marco Alegre-Sancho, Juan Jose Truchetet, Marie-Elise Braun-Moscovici, Yolanda Iannone, Florenzo Novikov, Pavel I. Lescoat, Alain Siegert, Elise Castellví, Ivan Airò, Paolo Vettori, Serena De Langhe, Ellen Hachulla, Eric Erler, Anne Ananieva, Lidia P. Krusche, Martin López-Longo, F. J. Distler, Jörg H. W. Hunzelmann, Nicolas Hoffmann-Vold, Anna-Maria Riccieri, Valeria Hsu, Vivien M. Pozzi, Maria Rosa Ancuta, Codrina Rosato, Edoardo Mihai, Carina Kuwana, Masataka Saketkoo, Lesley Ann Chizzolini, Carlo Hesselstrand, Roger Ullman, Susanne Yavuz, Sule Rednic, Simona Caimmi, Cristian Bloch-Queyrat, Coralie Allanore, Yannick Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) EUSTAR
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3.

001-es BibID:BIBFORM072620
035-os BibID:(WoS)000412506700023 (Scopus)85030983267
Első szerző:Elhai, Muriel
Cím:Mapping and predicting mortality from systemic sclerosis / Elhai Muriel, Meune Christophe, Boubaya Marouane, Avouac Jérôme, Hachulla Eric, Balbir-Gurman Alexandra, Riemekasten Gabriela, Airò Paolo, Joven Beatriz, Vettori Serena, Cozzi Franco, Ullman Susanne, Czirják László, Tikly Mohammed, Müller-Ladner Ulf, Caramaschi Paola, Distler Oliver, Iannone Florenzo, Ananieva Lidia P., Hesselstrand Roger, Becvar Radim, Gabrielli Armando, Damjanov Nemanja, Salvador Maria J., Riccieri Valeria, Mihai Carina, Szücs Gabriella, Walker Ulrich A., Hunzelmann Nicolas, Martinovic Duska, Smith Vanessa, Müller Carolina de Souza, Montecucco Carlo Maurizio, Opris Daniela, Ingegnoli Francesca, Vlachoyiannopoulos Panayiotis G., Stamenkovic Bojana, Rosato Edoardo, Heitmann Stefan, Distler Jörg H. W., Zenone Thierry, Seidel Matthias, Vacca Alessandra, Langhe Ellen De, Novak Srdan, Cutolo Maurizio, Mouthon Luc, Henes Jörg, Chizzolini Carlo, Mühlen Carlos Alberto von, Solanki Kamal, Rednic Simona, Stamp Lisa, Anic Branimir, Santamaria Vera Ortiz, Santis Maria De, Yavuz Sule, Sifuentes-Giraldo Walter Alberto, Chatelus Emmanuel, Stork Jiri, Laar Jacob van, Loyo Esthela, García de la Peňa Lefebvre Paloma, Eyerich Kilian, Cosentino Vanesa, Alegre-Sancho Juan Jose, Kowal-Bielecka Otylia, Rey Grégoire, Matucci-Cerinic Marco, Allanore Yannick, EUSTAR group
Dátum:2017
ISSN:0003-4967
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
systemic sclerosis
Megjelenés:Annals Of The Rheumatic Diseases. - 76 : 11 (2017), p. 1897-1905. -
További szerzők:Meune, Christophe Boubaya, Marouane Avouac, Jérôme Hachulla, Eric Balbir Gurman, Alexandra Riemekasten, Gabriela Airò, Paolo Joven, Beatriz Vettori, Serena Cozzi, Franco Ullman, Susanne Czirják László Tikly, Mohammed Müller-Ladner, Ulf Caramaschi, Paola Distler, Oliver Iannone, Florenzo Ananieva, Lidia P. Hesselstrand, Roger Becvar, Radim Gabrielli, Armando Damjanov, Nemanja Salvador, Maria J. Riccieri, Valeria Mihai, Carina Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Walker, Ulrich Hunzelmann, Nicolas Martinovic, Duska Smith, Vanessa Müller, Carolina de Souza Montecucco, Carlo Maurizio Opris, Daniela (1976-) (reumatológus) Ingegnoli, Francesca Vlachoyiannopoulos, Panayiotis G. Stamenkovic, Bojana Rosato, Edoardo Heitmann, Stefan Distler, Jörg H. W. Zenone, Thierry Seidel, Matthias Vacca, Alessandra Langhe, Ellen De Novak, Srdan Cutolo, Maurizio Mouthon, Luc Henes, Jörg Chizzolini, Carlo Mühlen, Carlos Alberto von Solanki, Kamal Rednic, Simona Stamp, Lisa Anic, Branimir Santamaria, Vera Ortiz Santis, Maria De Yavuz, Sule Sifuentes-Giraldo, Walter Alberto Chatelus, Emmanuel Stork, Jiri Laar, Jacob M. van Loyo, Esthela García de la Peňa Lefebvre, Paloma Eyerich, Kilian Cosentino, Vanesa Alegre-Sancho, Juan Jose Kowal-Bielecka, Otylia Rey, Grégoire Matucci-Cerinic, Marco Allanore, Yannick EUSTAR group
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4.

001-es BibID:BIBFORM104159
035-os BibID:(WOS)000846880900001
Első szerző:Garaiman, Alexandru
Cím:Use of platelet inhibitors for digital ulcers related to systemic sclerosis : EUSTAR study on derivation and validation of the DU-VASC model / Garaiman Alexandru, Steigmiller Klaus, Gebhard Catherine, Mihai Carina, Dobrota Rucsandra, Bruni Cosimo, Matucci-Cerinic Marco, Henes Jörg, de Vries-Bouwstra Jeska, Smith Vanessa, Doria Andrea, Allanore Yannick, Dagna Lorenzo, Anic Branimir, Montecucco Carlomaurizio, Kowal-Bielecka Otylia, Martin Mickael, Tanaka Yoshiya, Hoffmann-Vold Anna-Maria, Held Ulrike, Distler Oliver, Becker Mike Oliver, EUSTAR Collaborators
Dátum:2023
ISSN:1462-0324 1462-0332
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
systemic sclerosis
digital ulcers
Megjelenés:Rheumatology. - 62 : SI (2023), p. SI91-SI100. -
További szerzők:Steigmiller, Klaus Gebhard, Catherine Mihai, Carina Dobrota, Rucsandra Bruni, Cosimo Matucci-Cerinic, Marco Henes, Jörg de Vries-Bouwstra, Jeska Smith, Vanessa Doria, Andrea Allanore, Yannick Dagna, Lorenzo Anic, Branimir Montecucco, Carlo Maurizio Kowal-Bielecka, Otylia Martin, Mickael Tanaka, Yoshiya Hoffmann-Vold, Anna-Maria Held, Ulrike Distler, Oliver Becker, Mike Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) EUSTAR
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5.

001-es BibID:BIBFORM111057
035-os BibID:(scopus)85150001158 (wos)000962801600001
Első szerző:Hoffmann-Vold, Anna-Maria
Cím:Cohort Enrichment Strategies for Progressive Interstitial Lung Disease in Systemic Sclerosis From European Scleroderma Trials and Research / Hoffmann-Vold Anna-Maria, Brunborg Cathrine, Airo Paolo, Ananyeva Lidia P., Czirják László, Guiducci Serena, Hachulla Eric, Li Mengtao, Mihai Carina, Riemekasten Gabriela, Sfikakis Petros P., Valentini Gabriele, Kowal-Bielecka Otylia, Allanore Yannick, Distler Oliver, EUSTAR collaborators
Dátum:2023
ISSN:0012-3692
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Chest. - 163 : 3 (2023), p. 586-598. -
További szerzők:Brunborg, Cathrine Airò, Paolo Ananyeva, Lidia P. Czirják László Guiducci, Serena Hachulla, Eric Li, Mengtao Mihai, Carina Riemekasten, Gabriela Sfikakis, Petros P. Valentini, Gabriele Kowal-Bielecka, Otylia Allanore, Yannick Distler, Oliver Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) EUSTAR
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6.

001-es BibID:BIBFORM057704
035-os BibID:(WoS)000373403800019 (Scopus)84930163748
Első szerző:Mihai, Carina
Cím:Digital ulcers predict a worse disease course in patients with systemic sclerosis / Carina Mihai, Robert Landewé, Désirée van der Heijde, Ulrich A. Walker, Paul I. Constantin, Ana Maria Gherghe, Ruxandra Ionescu, Simona Rednic, Yannick Allanore, Jérôme Avouac, László Czirják, Eric Hachulla, Gabriela Riemekasten, Franco Cozzi, Paolo Airò, Maurizio Cutolo, Ulf Mueller-Ladner, Marco Matucci-Cerinic, EUSTAR co-authors
Dátum:2016
ISSN:0003-4967
Megjegyzések:OBJECTIVE: Systemic sclerosis (SSc) is a systemic autoimmune disease with high morbidity and significant mortality. There is a great need of predictors that would allow risk stratification of patients with SSc and ultimately initiation of treatment early enough to ensure optimal clinical results. In this study, we evaluated whether a history of digital ulcers (HDU) at presentation may be a predictor of vascular outcomes and of overall clinical worsening and death in patients with SSc. METHODS: Patients from the EULAR Scleroderma Trials and Research (EUSTAR) database, satisfying at inclusion the 1980 American College of Rheumatology classification criteria for SSc, who had a follow-up of at least 3 years since baseline or who have died, were included in the analysis. HDU at presentation as a predictor of disease worsening or death was evaluated by Cox proportional hazards regression analysis. RESULTS: 3196 patients matched the inclusion criteria (male sex 13.2%, 33.4% diffuse subset). At presentation, 1092/3196 patients had an HDU (34.1%). In multivariable analysis adjusting for age, gender and all parameters considered potentially significant, HDU was predictive for the presence of active digital ulcers (DUs) at prospective visits (HR (95% CI)): 2.41 (1.91 to 3.03), p<0.001, for an elevated systolic pulmonary arterial pressure on heart ultrasound (US-PAPs):1.36 (1.03 to 1.80), p=0.032, for any cardiovascular event (new DUs, elevated US-PAPs or LV failure): 3.56 (2.26 to 5.62), p<0.001, and for death (1.53 (1.16 to 2.02), p=0.003). CONCLUSIONS: In patients with SSc, HDU at presentation predicts the occurrence of DUs at follow-up and is associated with cardiovascular worsening and decreased survival. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
systemic sclerosis
Megjelenés:Annals of The Rheumatic Diseases. - 75 : 4 (2016), p. 681-686. -
További szerzők:Landewé, Robert Heijde, Désirée van der Walker, Ulrich Constantin, Paul I. Gherghe, Ana Maria Ionescu, Ruxandra Rednic, Simona Allanore, Yannick Avouac, Jérôme Czirják László Hachulla, Eric Riemekasten, Gabriela Cozzi, Franco Airò, Paolo Cutolo, Maurizio Mueller-Ladner, Ulf Matucci-Cerinic, Marco Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) EUSTAR
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