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001-es BibID:	BIBFORM110962
035-os BibID:	(Scopus)85160773220 (WoS)000995614500001
Első szerző:	Polyák András
Cím:	Implant Imaging : Perspectives of Nuclear Imaging in Implant, Biomaterial, and Stem Cell Research / Andras Polyak, Zita Képes, György Trencsényi
Dátum:	2023
ISSN:	2306-5354
Megjegyzések:	Until now, very few efforts have been made to specifically trace, monitor, and visualize implan-tations, artificial organs, and bioengineered scaffolds for tissue engineering in vivo. While mainly X-Ray, CT, and MRI methods have been used for this purpose, the applications of more sensitive, quantitative, specific, radiotracer-based nuclear imaging techniques remain a challenge. As the need for biomaterials increases, so does the need for research tools to evaluate host responses. PET (positron emission tomography) and SPECT (single photon emission computer tomography) techniques are promising tools for the clinical translation of such regenerative medicine and tissue engineering efforts. These tracer-based methods offer unique and inevitable support, providing specific, quantitative, visual, non-invasive feedback on implanted biomaterials, devices, or trans-planted cells. PET and SPECT can improve and accelerate these studies through biocompatibility, inertivity, and immune-response evaluations over long investigational periods at high sensitivities with low limits of detection. The wide range of radiopharmaceuticals, the newly developed specific bacteria, and the inflammation of specific or fibrosis-specific tracers as well as labeled individual nanomaterials can represent new, valuable tools for implant research. This review aims to sum-marize the opportunities of nuclear-imaging-supported implant research, including bone, fibrosis, bacteria, nanoparticle, and cell imaging, as well as the latest cutting-edge pretargeting methods.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk implant biomaterial tissue engineering bioengineering stem cell nanoparticles liposomes PET SPECT CT
Megjelenés:	Bioengineering-Basel. - 10 : 5 (2023), p. 1-14. -
További szerzők:	Képes Zita (1991-) (orvos) Trencsényi György (1978-) (biológus, biokémikus, molekuláris biológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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