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001-es BibID:BIBFORM073194
Első szerző:Nemes Judit (fogszakorvos)
Cím:Retrospective analysis of oral squamous cell carcinoma focusing on young adults in Northeastern Hungary / Judit A. Nemes, Róbert Boda, Pál Redl, Ildikó J. Márton
Megjegyzések:Aim The purpose of this study was to define the profile of patients with oral squamous cell carcinoma (OSCC) with an emphasis on an adult population in Northeastern Hungary. Materials and methods Histopathological reports of 119 cases of OSCC treated at the Department of Pathology, University of Debrecen (Hungary) were retrospectively evaluated, and the data regarding age, gender, oral site affected, clinical and pathological features and risk factors were recorded and statistically analyzed for differences between patients younger and older than 45 years of age. Results Twenty-two patients (18.5%) were 45 years of age or below, the male:female ratio was 3.4:1. The floor of the mouth was the most frequent cancer site in the young age-group (50%), while lip (33%) was in the older group. The younger patients were diagnosed at an advanced stage (p=0.022), with more regional and distant metastases (p=0.028). The 5-year overall survival rate was lower, though not significantly, in the younger group (27.3% vs. 41.2%). Risk factors such as tobacco use and excessive alcohol consumption were present in 72.7% of the younger patients. Smoking habit significantly correlated with younger age (p=0.031). Conclusion OSCC is a serious oral health problem in Northeastern Hungary, as the rate of the patients under the age of 45 years is extremely high. In this age group we found a decreasing overall survival time along with increasing intensity of risk habits. As the majority of the young patients presented with OSCC in advanced stages, early detection and treatment together with cessation of tobacco and alcohol abuse may improve patients' survival.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
oral cancer
squamous cell carcinoma
Oral squamous cell carcinoma
OSCC incidence
prevalence of OSCC in Hungary
Megjelenés:Italian journal of Dental Medicine 2 : 3 (2017), p. 76-82. -
További szerzők:Boda Róbert (1978-) (fogszakorvos) Redl Pál (1953-) (szájsebész) Márton Ildikó (1954-) (fogszakorvos)
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