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001-es BibID:	BIBFORM015615
035-os BibID:	10946767
Első szerző:	Felszeghy Szabolcs Béla (fogorvos, anatómus, kötőszövetbiológus)
Cím:	Quantitative image analysis of hyaluronan expression in human tooth germs / Felszeghy S., Hyttinen, M., Tammi, R., Tammi, M., Modis L.
Dátum:	2000
ISSN:	0909-8836 (Linking)
Megjegyzések:	The expression of hyaluronan in human tooth germs was studied by using abiotinylated hyaluronan-binding complex and quantitative digital image analysis.At the cap stage, dental papilla exhibited a moderate staining, while intensereaction was observed in the apical portion of presecretory ameloblasts, stellatereticulum, and in dental basement membrane. When the enamel and dentine matricesstarted to develop, a strong hyaluronan reaction was evident in the young enameland the apical portion of secretory ameloblasts. No hyaluronan could be detectedin the secretory ameloblasts and enamel matrix of the early (9-wk-old) post-natalstage. It is concluded that hyaluronan may play a transitory role in the earlyphase of the development of the enamel matrix organization. A very weak signalwas observed in the wall of dentin tubules, whereas the rest of the dentinematrix was not stained. The odontoblasts and the pulp were also moderatelystained, and these reactions gradually decreased with age, suggesting thathyaluronan may also contribute to the development of dentine matrix and pulp.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban 0 (Extracellular Matrix Proteins) 9004-61-9 (Hyaluronic Acid) Ameloblasts/metabolism Amelogenesis/physiology Dental Papilla/embryology/metabolism Embryonic and Fetal Development Enamel Organ/embryology/metabolism Extracellular Matrix Proteins/metabolism Humans Hyaluronic Acid/metabolism Image Processing, Computer-Assisted Immunoenzyme Techniques Protein Binding Tooth Germ/embryology/metabolism egyetemen (Magyarországon) készült közlemény
Megjelenés:	European journal of oral sciences. - 108 : 4 (2000), p. 320-326. -
További szerzők:	Hyttinen, Mikka Tammi, Raija (kutatóorvos) Tammi, Markku (kutatóorvos) Módis László (1939-) (anatómus, kötőszövetbiológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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