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1.

001-es BibID:BIBFORM091543
Első szerző:Csikós Anett (biomérnök, biológia-földrajz tanár)
Cím:Evaluation of zinc and copper levels in vaginal tissues and whole blood : correlation with age / Csikós Anett, Kozma Bence, Baranyai Edina, Miklós Ida, Larson Kindra, Póka Róbert, Takacs Peter
Dátum:2021
ISSN:1472-6874
Megjegyzések:Background: Zinc and copper are essential trace elements and play a crucial role in the homeostasis of connective tissues. In this study, we aimed to define zinc and copper levels in the vaginal tissue and establish whether a correlation exists between the zinc and copper levels either or both in whole blood or vaginal tissue samples and whether the finding correlates with the age of the patient or at least with her menopausal status. Methods: We collected whole blood and vaginal tissue samples from 32 women and measured their zinc and copper levels by inductively coupled plasma optical emission spectrometry. We have performed Student's t test to evaluate the differences in the mean levels of trace elements and multiple regression to evaluate the association between vaginal tissue zinc/copper levels and age, menopausal status, number of vaginal deliveries, and zinc/copper blood levels. Results: Zinc levels were significantly higher in both the vaginal tissues and whole blood samples than copper levels (p?<?0.01). In the vaginal tissue samples, a strong positive correlation could be detected between zinc and copper levels (r?=?0.82, p?<?0.01). In the vaginal tissue, a negative correlation was found for zinc and copper levels with the age of women (r?=???0.27, p?=?0.04 and r?=???0.56, p?<?0.01). Multiple linear regression model (age, menopausal status, vaginal delivery and copper/zinc blood levels) showed that only age remained a significant predictor for zinc and copper vaginal tissues levels (p?=?0.03, 95% CI ??2.28 to ??0.06; p?=?0.004, 95% CI ??1.76 to ??0.34). Conclusions: Zinc and copper levels in the vaginal tissue decline with age. Out of the examined variables (age, menopausal status, vaginal delivery, and copper/zinc levels), only age is a significant predictor of vaginal zinc/copper levels.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Ageing
Cooper
ICP-OES
Vagina
Whole blood
Zinc
Megjelenés:BMC Women's Health. - 21 : 1 (2021), p. 1-7. -
További szerzők:Kozma Bence (1982-) (szülész-nőgyógyász) Baranyai Edina (1987-) (környezetkutató) Miklós Ida (1962-) (biológus) Larson, Kindra Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász)
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Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM084850
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:Association between pelvic organ prolapse types and levator-urethra gap as measured by 3D transperineal ultrasound / Kozma Bence, Larson Kindra, Scott Lauren, Cunningham Tina, Abuhamad Alfred, Póka Róbert, Takacs Péter
Dátum:2018
ISSN:0937-3462
Megjegyzések:Introduction: Pelvic organ prolapse (POP) is a common condition affecting many women. During delivery, the components of the levator ani muscle undergo significant distention and stretching leading to muscle damage 10-25% of the time. Injury to the pelvic floor muscles can result in floor dysfunction like POP or stress urinary incontinence. Levator ani defects can be diagnosed clinically by vaginal palpation or using transperineal ultrasound. Previously the standard sonographic diagnosis of levator avulsion required observation of an abnormal insertion of the muscle on tomographic ultrasound imaging (TUI). But most recently the measurement of the levator?urethra gap (LUG) has been described as a quantitative tool in this regard. LUG is the distance between the center of the urethral lumen and insertion of the levator on the inferior pubic ramus, determined bilaterally, in axial slices on transperineal 3D ultrasound. The measurement of LUG is reproducible and an abnormal LUG (?25mm) has been strongly associated with avulsion diagnosed by vaginal palpation. Objectives: To evaluate the association between POP types and LUG as measured by 3D transperineal tomographic ultrasound (TPUS). Methods: A retrospective study was carried out on ninety-eight women with symptomatic POP. 3D TPUS images and Pelvic Organ Prolapse Quantification coordinates were reviewed. Each vaginal compartment was staged for the degree of prolapse, and total number of involved compartments identified. LUG was measured on 3D tomographic ultrasound images as the distance between the center of the urethra and the levator insertion bilaterally. Based upon prior studies, an abnormal LUG?25mm indicated levator avulsion. LUG and presence or absence of unilateral/bilateral avulsions was analyzed with reference to the clinical diagnosis of prolapse [single vs. multi compartment, and mild (stage II) vs. severe (stage III-IV)]. Generalized logit models were used to evaluate the association between avulsion and prolapse type and stage. Results: The LUG was significantly larger in women with multi compartment compared to single compartment POP (28.9?4.1mm vs. 22.7 ?4.1mm, P<0.01). Similarly, LUG was significantly larger in women with severe (stage III-IV) compared to mild POP (stage II) (28.8 ?4.7mm vs. 23.3?4.5mm, P<0.01). Women with severe prolapse were 32 times more likely than women with mild prolapse to have bilateral levator avulsion. Those with POP involving all three vaginal compartments were 76 times more likely than single compartment POP to have bilateral levator avulsions. Conclusions: Bilateral levator ani avulsion as diagnosed by LUG measurements of ?25mm at rest is associated with multi compartment, sever prolapse.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:International Urogynecology Journal. - 29 : S1 (2018), p. 174. -
További szerzők:Larson, Kindra Scott, Lauren Cunningham, Tina D. Abuhamad, Alfred Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász)
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Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM084851
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:Fractional CO2 laser treatment significantly increases vaginal fluid zinc and copper level / Kozma Bence, Takács Péter, Póka Róbert
Dátum:2018
ISSN:0937-3462
Megjegyzések:Introduction: Fractional CO2 laser treatment became a popular treatment option for postmenopausal vaginal atrophy. The laser therapy creates microinjuries of the vagina and subsequent remodeling leads to the reorganization of the extracellular matrix of the vagina. Zinc and copper are essential trace elements and both play a vital role in tissue remodeling. Both zinc and copper functions as a cofactor for many enzymes participating in the composition of the extracellular matrix. Objectives: To evaluate the effect of the Mona Lisa Touch CO2 laser treatment on postmenopausal women vaginal fluid trace element content: zinc and copper. Both zinc and copper play a pivotal role as a cofactor for several enzymes responsible for tissue remodeling. Our hypothesis was that increased tissue remodeling secondary to vaginal laser treatment will result in altered vaginal fluid zinc and copper content. Materials and Methods: Twenty-seven postmenopausal women with genitourinary symptoms of menopause were enrolled and underwent vaginal laser treatment. Mona Lisa Touch is a functional vaginal rejuvenation treatment based on a special fractional CO2 laser, specifically created for the vaginal mucosa. Patients received three vaginal laser treatments with the 360 degree probe 4-6 weeks apart. Vaginal fluid was collected in a standardized fashion. Extreme care was exercised to avoid any possible contamination. Only single use plastic speculums free of trace elements were used. Atomic absorption spectroscopy was used to determine the vaginal fluid zinc and copper content. Paired t-test was used to compare the before and after treatment results. Results: All patients were in menopause. The average age was 58 ? 9 years. The mean zinc level was 0.08 ? 0.08 mg/L before the initiation of the first treatment. After the first treatment the vaginal zinc level did not change significantly (0.08 ? 0.05 mg/L) But after the second laser treatment vaginal fluid zinc level was significantly higher 0.11 ? 0.07 mg/L (P< 0.01) and the third treatment increased vagina zinc levels even further to 0.16 ? 0.08 mg/L (P<0.01). The mean copper level was 0.008 ? 0.009 mg/L before the initiation of the first treatment. After the first and second treatment the vaginal copper level did not change significantly (0.010 ? 0.011 mg/L and 0.009 ? 0.008) But after the third laser treatment vaginal fluid copper level was significantly higher 0.016 ? 0.014 mg/L (P=0.04). Zinc content of the vaginal fluid was ten folds higher than copper levels. Conclusion: Microablative fractional CO2 vaginal laser treatment significantly increases vaginal fluid zinc content. Zinc and copper levels increased by two folds after the third laser treatment. Elevated zinc and copper levels in the vaginal fluid is most likely occurs secondary to the increased vaginal remodeling.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:International Urogynecology Journal. - 29 : S1 (2018), p. 174-175. -
További szerzők:Takács Péter (1968-) (szülész-nőgyógyász) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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4.

001-es BibID:BIBFORM084853
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:The effects of fractional CO2 laser treatment on the symptoms of pelvic floor dysfunctions and vulvovaginal atrophy / Kozma Bence, Takács Péter, Sipos Attila Gergely, Póka Róbert
Dátum:2018
ISSN:0937-3462
Megjegyzések:Introduction: Vaginal laser treatment became a popular treatment modality for genitourinary syndrome of menopause. However scientific data is limited regarding the effects of laser treatment on different pelvic floor dysfunctions. Objectives: To evaluate the effect of the Mona Lisa Touch CO2 laser treatment on postmenopausal women vulvovaginal and pelvic floor dysfunction symptoms. Methods: Forty-three postmenopausal women were enrolled and underwent vaginal laser treatment with. Mona Lisa Touch. Patients received three vaginal laser treatments with the 360 degree probe 4-6 weeks apart. Pelvic Organ Prolapse Distress Inventory 6 (POPDI-6), Colorectal?Anal Distress Inventory 8 (CRADI-8) and Urinary Distress Inventory 6 (UDI-6) validated questionnaires were filled out by each patient before each session and 4 weeks after the final treatment. Vaginal Health Index (Elasticity, Fluid Secretion, pH, Epithelial mucosa, Moisture) was calculated before each session and 4 weeks after the final treatment. In addition, patients were asked to fill out a Visual Analog Scale (1-10, lower scores indicates less bother) on vaginal pain, dryness, burning, itching, dyspareunia and dysuria. Paired ttest was used to compare the before and after treatment results. Results: All patients were in menopause. The average age was 57?10 years. POPD-6 standardized scores were not significantly different after the first treatment (20 ?19 vs. 14?11 after the first treatment). But after the second treatment there was a significant improvement in the standardized score to 11?12 ( P=0.02). After the third treatment the score was even lower 10?13 (P=0.01). CRADI-8 standardized scores did not change significantly after three laser treatment (16 ?18 vs. 13?17 after the 1st treatment/13?16 after the 2nd treatment/ 12?18 after the 3rd treatment). UDI-6 standardized scores were not significantly different after the first laser treatment (32?23 vs. 26?23 after the first treatment). But after the second treatment there was a significant improvement in the standardized score to 25 ? 20 ( P=0.03). The Vaginal Health Index was 15?5 before and 17?4 after the first treatment, 19?5 after the second and 21?4 after the third treatment. VHI was significantly improved after each treatment (P<0.01). The largest incremental change occurred in vaginal moisture, followed by vaginal fluid and elasticity. The patient reported combined Visual Analog Score (VAS) was 16?16 before and 9?12 after the first treatment, 6 ? 9 after the second and 3 ? 8 after the third treatment. VAS was significantly lower (P<0.01) after each laser treatment. The largest improvement occurred after the first laser treatment, but each additional treatment added additional symptoms relief. Conclusion: CO2 vaginal laser treatment significantly improves patient reported urinary and pelvic organ prolapse bother. The minimum of two laser treatments were needed to achieve a significant benefit. In addition, CO2 vaginal laser treatment significantly improves both the patient reported subjective symptoms and the Vaginal Health Index in postmenopausal women even after a single laser treatment.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
folyóiratcikk
Megjelenés:International Urogynecology Journal. - 29 : S1 (2018), p. 174. -
További szerzők:Takács Péter (1968-) (szülész-nőgyógyász) Sipos Attila Gergely (1990-) (szülész-nőgyógyász) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus)
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

5.

001-es BibID:BIBFORM081140
035-os BibID:(scopus)85072931858 (wos)000489109700002
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:A hüvelyi CO2-lézer-kezelés rövid távú hatásai a menopausalis genitourinalis szindróma tüneteire / Kozma Bence, Póka Róbert, Sipos Attila, Ács Nándor, Takács Péter
Dátum:2019
ISSN:0030-6002 1788-6120
Tárgyszavak:Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban
folyóiratcikk
Megjelenés:Orvosi Hetilap. - 160 : 41 (2019), p. 1617-1622. -
További szerzők:Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Sipos Attila Gergely (1990-) (szülész-nőgyógyász) Ács Nándor Takács Péter (1968-) (szülész-nőgyógyász)
Pályázati támogatás:GINOP-2.1.1-15-2016-00783
GINOP
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Intézményi repozitóriumban (DEA) tárolt változat
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6.

001-es BibID:BIBFORM075687
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:The Effects of Heat Exposure on Vaginal Smooth Muscle Cells : elastin and Collagen Production / Bence Kozma, Keith Candiotti, Róbert Póka, Péter Takács
Dátum:2018
ISSN:0378-7346
Megjegyzések:Aims: To evaluate smooth muscle cells (SMCs) proliferation and elastin and collagen production after heat exposure (65 ? C). Methods: Samples were taken from the anterior vaginal wall, SMCs were cultured, and heated to 65 ? C for 30 and 60 s. Cell proliferation was assessed; tropoelastin and collagen production was measured. Results: Heat does not affect SMC proliferation at 65 ? C neither at 30 nor at 60 s. Surfacedeposited elastin level was significantly increased after heat exposure (mean ? SD, 30 s 155 ? 5% of control [p < 0.01] and 60 s 516 ? 40% of control [p < 0.01]). Tropoelastin levels in the culture media were significantly lower after 60 s of heat exposure (mean ? SD, 30 s 102 ? 5% of control [p = ns] and 60 s 70 ? 2% of control [p = 0.04]). Significant increase in surface-deposited collagen production was found (mean ? SD, 30 s 170 ? 6% of control [p < 0.01] and 60 s 123 ? 6% of control [p < 0.01]), but no such elevation was measured in the media after heat exposure (mean ? SD, 30 s 120 ? 20% of control [p = ns] and 60 s 100 ? 20% of control [p = ns]). Conclusion: When SMCs are exposed to heat there is significant elevation in collagen and elastin production. Changes in the composition of the extracellular matrix after heat exposure may contribute to vaginal wall remodeling.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Gynecologic And Obstetric Investigation. - 83 : 3 (2018), p. 247-251. -
További szerzők:Candiotti, Keith Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász)
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

7.

001-es BibID:BIBFORM075686
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:Association between pelvic organ prolapse types and levator-urethra gap as measured by 3D transperineal ultrasound / Bence Kozma, Kindra Larson, Lauren Scott, Tina D. Cunningham, Alfred Abuhamad, Robert Poka, Peter Takacs
Dátum:2018
ISSN:0278-4297
Megjegyzések:Objectives : To evaluate the association between pelvic organ prolapse (POP)types and levator-urethra gap (LUG) as measured by 3-dimensional transperineal tomographic ultrasound. Methods : A retrospective study was carried out on 98 women with symptomatic POP. Three-dimensional transperineal tomographic ultrasound images and POP quantification coordinates were reviewed. Each vaginal compartment was staged for the degree of prolapse, and total number of involved compartments identified. LUG was measured on 3-dimensional tomographic sonograms as the distance between the center of the urethra and the levator insertion bilaterally. Based on prior studies, an abnormal LUG of 25mm or greater indicated levator avulsion. The LUG and the presence or absence of unilateral/bilateral avulsions was analyzed with reference to the clinical diagnosis of prolapse (single versus multicompartment, and mild [stage II] versus severe [stage III?IV]). Generalized logit models were used to evaluate the association between avulsion and prolapse type and stage. Results ? The LUG was substantially larger in women with multicompartment compared to single-compartment POP (28.964.1mm versus 22.764.1mm, P<.01). Similarly, LUG was substantially larger in women with severe (stage III?IV) compared to mild (stage II) POP (28.864.7mm versus 23.364.5 mm, P<.01). Women with severe prolapse were 32 times more likely than women with mild prolapse to have bilateral levator avulsion. Those with POP involving all 3 vaginal compartments were 76 times more likely than single-compartment POP to have bilateral levator avulsions. Conclusions : Bilateral levator ani avulsion as diagnosed by LUG measurements of 25mm or greater at rest is associated with multicompartment, severe prolapse.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
levator ani avulsion
levator-urethra gap
pelvic organ prolapse
transperineal ultrasound
Megjelenés:Journal Of Ultrasound In Medicine. - 37 : 12 (2018), p. 2849-2854. -
További szerzők:Larson, Kindra Scott, Lauren Cunningham, Tina D. Abuhamad, Alfred Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász)
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

8.

001-es BibID:BIBFORM075682
035-os BibID:(scopus)85055071630 (wos)000447882200001
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:A percutan nervus tibialis stimuláció szerepe egyes kismedencei kórképek kezelésében / Kozma Bence, Majoros Attila, Pytel Ákos, Póka Róbert, Takács Péter
Dátum:2018
ISSN:0030-6002 1788-6120
Megjegyzések:A percutan nervus tibialis stimuláció (PTNS) a legegyszerűbb, legkevésbé invazív és jól tolerálható neuromodulációs eljárás az alsó húgyutak és a székletürítés működését befolyásoló terápiás elektrofiziológiai technikák között. A PTNS során a medencefenéki izmok és a húgyhólyag afferens idegeinek stimulációja történik a sacralis plexuson keresztül (S2?4) a nervus tibialis posterior felől egyszer használatos vékony tűelektróda és többször használatos stimulátor segítségével. A széles körű klinikai használat ellenére hatásmechanizmusa nem pontosan ismert. Hatásosnak tekinthető túlműködő hólyag szindróma kezelése során, alkalmazása az Európai Urológiai Társaság vizeletincontinentia-irányelvének megfelelően javasolt antimuszkarinterápiára refrakter nőbetegek esetében. Túlműködő hólyagszindrómában kezelési hatékonysága a sacralis ideg neuromudulációjához hasonló. 2003 óta alkalmazzák székletincontinentia terápiájaként, szerepe azonban a megfelelő vizsgálatok hiánya miatt egyelőre kérdéses. A hagyományos kezelési lépések hatástalansága esetén a krónikus kismedencei fájdalom terápiájában szintén szerephez jut a PTNS. Jelentős mellékhatás a PTNS használata során nem került leírásra.
Tárgyszavak:Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Orvosi Hetilap. - 159 : 43 (2018), p. 1735-1740. -
További szerzők:Majoros Attila Pytel Ákos Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász)
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

9.

001-es BibID:BIBFORM020020
Első szerző:Kozma Bence (szülész-nőgyógyász)
Cím:Spontaneous and induced preterm birth have different obstetric characteristics and risk factors / Kozma Bence, Póka Róbert
Dátum:2011
Megjegyzések:Spontaneous and induced preterm births have different obstetric characteristics and risk factorsBence Kozma, Robert PokaDept. Obstet. Gynaecol. University of Debrecen, Medical and Health Science Center, HungaryIntroduction: Preterm birth (PTB) is often described as a single entity. Prevention is based on identification and elimination of risk factors that are observed in the entire pregnant population delivering before 37 weeks gestation. PTB is mostly viewed as an outcome despite the fact that, in many cases, it is a method of obstetric intervention to reduce fetal, maternal and neonatal morbidity and mortality. Therefore, we decided to test the notion that there might be important differences between spontaneous and induced cases of PTB with regards to both risk factors and outcome measures.Methods and patients: Retrospective analysis of 1500 consecutive cases was carried out by collecting demographic, obstetric and outcome data. PTB was defined as delivery before the 37th completed gestational week based on Naegele calculation corrected by first trimester CRL measurement. Comparisons were made between cases of spontaneous and induced deliveries. The delivery was considered spontaneous if tocolysis was required to attain time for fetal therapy or there was no need for measures aiming at cervical ripening or inducing uterine activity with oxytocin. Continuous variables were compared by t-test and the frequency of categorical variables were compared by ?2-test.Results: According to our selection criteria 571 cases were spontaneous and 929 cases were induced PTBs. The mean age and prepregnancy weight of patients with induced and spontaneous delivery were significantly different (30,2 vs 28,4 years; 68,8 vs 64,4 kg). There was no difference between the two groups in the number of spontaneous and artificial abortions. Among multiparous patients there was a significant difference in the frequency of previous Caesarean section between induced and spontaneous cases of PTB (82/163 vs 30/141). No differences were found between our groups with regards to history of hypertension, asthma, diabetes and renal disease but significantly more patients were smokers among cases with induced PTB (92/565 vs 227/916). In the index pregnancy, significantly more patients had preeclampsia in the induced group but there was no difference in the frequency of asthma, diabetes, renal disease and urinary tract infection. However, preterm premature rupture of membranes was significantly less common in the induced group then among spontaneous PTBs (213/571 vs 567/929). Caesarean frequency was significantly higher in the induced group compared to that in spontaneous PTBs (402/571 vs 312/928). Despite mean gestational age at birth was not different in the two groups (32,7 vs 33,0 weeks), the mean birthweight was significantly higher in the spontaneous group than in induced PTBs (2173 vs 1979 g).Conclusion: Induced PTBs have significantly different demographic and obstetric background as well as different outcome when compared to those of spontaneous PTBs. Our results show that a genome wide search for risk factors of preterm delivery may need to take these differences into account.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
preterm birth
risk factors
Megjelenés:Biopolymers and Cell. - 27 (2011), p. 101. -
További szerzők:Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Borító:

10.

001-es BibID:BIBFORM089120
Első szerző:Pákozdy Krisztina (szülész-nőgyógyász)
Cím:Vaginal elasticity is significantly decreased in vaginal atrophy / Pákozdy Krisztina, Sipos Attila G., Bombicz Mariann, Lampé Rudolf, Póka Róbert, Takacs Peter, Kozma Bence
Dátum:2020
ISSN:1530-0374
Megjegyzések:taa, km
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Elastography
Vulvovaginal atrophy
Vaginal wall
Vaginal cytology
Transvaginal ultrasound
Genitourinary syndrome of menopause
Megjelenés:Menopause. - 27 : 12 (2020), p. 1420-1424. -
További szerzők:Sipos Attila Gergely (1990-) (szülész-nőgyógyász) Bombicz Mariann (1987-) (gyógyszerész) Lampé Rudolf (1983-) (szülész-nőgyógyász) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Takács Péter (1968-) (szülész-nőgyógyász) Kozma Bence (1982-) (szülész-nőgyógyász)
Pályázati támogatás:GINOP-2.1.1-15-2016-00783
GINOP
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Intézményi repozitóriumban (DEA) tárolt változat
Borító:

11.

001-es BibID:BIBFORM081242
Első szerző:Sipos Attila Gergely (szülész-nőgyógyász)
Cím:The Effect of Fractional CO2 Laser Treatment on the Symptoms of Pelvic Floor Dysfunctions : pelvic Floor Distress Inventory-20 Questionnaire / Attila Gergely Sipos, Bence Kozma, Robert Poka, Kindra Larson, Peter Takacs
Dátum:2019
ISSN:0196-8092
Megjegyzések:Background and Objectives: To assess the improve- ment on pelvic floor distress (PFD)?related urogenital symptoms using validated questionnaires after intrava- ginal CO 2 laser treatment. Study Design/Materials and Methods: Forty postme- nopausal women with genitourinary symptoms of menopause (GSM) were enrolled into this prospective cohort study and underwent vaginal laser treatment using MonaLisa Touch ? fractional CO 2 laser system. Patients received three vaginal laser treatments with 360? probe 4 weeks apart. A three?component Pelvic Floor Distress Inventory (PFDI?20) validated question- naire was filled out by each patient before each session and 4 weeks after the final treatment. Wilcoxon rank sum test was used to compare the before and after treatment scores. Results: Pelvic Organ Prolapse Distress Inventory (POPDI?6) scores were not significantly different after the first treatment compared with baseline (mean ? standard deviation [SD], 21 ? 18 vs. 17 ? 15, P = 0.44). However, each subsequent treatment resulted in further, statistically significant improvement in symp- tom scores (14 ? 15, P = 0.03 and 13 ? 13, P = 0.01, after the second and third treatments, respectively). Simi- larly, Urinary Distress Inventory (UDI?6) scores were not significantly different after the first laser treat- ment (mean ? SD, 36 ? 25 vs. 29 ? 23, P = 0.36). After the second and third treatments there were significant improvement in the standardized scores (24 ? 20, P = 0.03 and 22 ? 21, P = 0.01). Colorectal?Anal Dis- tress Inventory (CRADI?8) scores did not change significantly after three laser treatments. Conclusions: Three sessions of microablative fractional CO 2 vaginal laser treatment significantly improves patient reported urinary and pelvic organ prolapse symptoms.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Lasers In Surgery And Medicine. - 51 : 10 (2019), p. 882-886. -
További szerzők:Kozma Bence (1982-) (szülész-nőgyógyász) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus) Larson, Kindra Takács Péter (1968-) (szülész-nőgyógyász)
Pályázati támogatás:GINOP-2.1.1-15-2016-00783
GINOP
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

12.

001-es BibID:BIBFORM085762
Első szerző:Takács Péter (szülész-nőgyógyász)
Cím:Randomized controlled trial for improved recovery of the pelvic floor after vaginal delivery with a specially formulated postpartum supplement / Takacs Peter, Kozma Bence, Lampé Rudolf, Sipos Attila, Poka Robert
Dátum:2020
ISSN:2287-8572 2287-8580
Megjegyzések:Objective To improve pelvic floor recovery after vaginal delivery with daily supplementation of a specially formulated postpartum recovery supplement. Methods Within 48 hours of vaginal delivery, primipara women were randomized in a 1:1 ratio to receive daily oral supplementation for 6 weeks with either a combination of regular prenatal vitamin (PNV), leucine (4 g/day), zinc (30 mg/day) and omega-3 fatty acid (900 mg/day) (treatment group), or only a PNV daily (control group). Co-primary outcomes were vaginal squeeze pressure as measured by perineometer and levator muscle injury as measured by transperineal 3-dimensional tomographic ultrasound at 6 weeks postpartum. Results Twenty-six women in the control group and 27 in the treatment group completed the trial. Weak pelvic floor muscle strength was significantly less frequent in the treatment group compared to the control group at 6 weeks after delivery (28% vs. 58%, P=0.03). Both right and left-sided levator-urethra gap was significantly larger in the control group compared to the treatment group indicating more levator injury being present in the control group at 6 weeks after delivery. Anterior vaginal wall prolapse at or beyond the hymenal ring was significantly more common in the control group compared to the treatment group (19% vs. 0%, P=0.02). Significantly more women reported bothersome bulge symptoms in the control group compared to the treatment group at 6 weeks postpartum (19% vs. 0%, P=0.02). Conclusion Postpartum women who received a specially formulated postpartum recovery supplement had improved recovery of the pelvic floor after vaginal delivery.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Postpartum
Pelvic floor
Omega-3 fatty acids
Zinc
Leucine
Megjelenés:Obstetrics & Gynecology Science. - 63 : 3 (2020), p. 305-314. -
További szerzők:Kozma Bence (1982-) (szülész-nőgyógyász) Lampé Rudolf (1983-) (szülész-nőgyógyász) Sipos Attila Gergely (1990-) (szülész-nőgyógyász) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus)
Pályázati támogatás:GINOP-2.1.1-15-2016-00783
GINOP
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
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