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001-es BibID:BIBFORM079736
035-os BibID:(cikkazonosító)1925 (PMID)31151318 (Scopus)85066955929 (WOS)000472132900053
Első szerző:Akinsolu, Folahanmi Tomiwa
Cím:Emerging resistance of neglected tropical diseases : a scoping review of the literature / Folahanmi T. Akinsolu, Priscilla O. Nemieboka, Diana W. Njuguna, Makafui N. Ahadji, Dora Dezso, Orsolya Varga
ISSN:1661-7827 1660-4601
Megjegyzések:Background: Antimicrobial resistance (AMR) is a global public health threat with the potential to cause millions of deaths. There has been a tremendous increase in the use of antimicrobials, stemming from preventive chemotherapy elimination and control programs addressing neglected tropical diseases (NTDs). This study aims to identify the frequency of drug resistance for 11 major NTDs and 20 treatment drugs within a specific period by systematically analyzing the study design, socio-demographic factors, resistance, and countries of relevant studies. Methods: Adhering to PRISMA guidelines, we performed systematic reviews of the major 11 NTDs to identify publications on drug resistance between 2000 and 2016. A quality assessment tool adapted for evaluating observational and experimental studies was applied to assess the quality of eligible studies. Results: One of the major findings is that six NTDs have information on drug resistance, namely human African trypanosomiasis, leishmaniasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, and trachoma. Many studies recorded resistance due to diagnostic tests, and few studies indicated clinical resistance. Although most studies were performed in Africa where there is the occurrence of several NTDs, there was no link between disease burden and locations of study. Conclusions: Based on this study we deduce that monitoring and surveillance systems need to be strengthened to enable the early detection of AMR and the mitigation of its global spread.
Tárgyszavak:Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban
antimicrobial resistance
drug resistance
neglected tropical diseases
Megjelenés:International Journal of Environmental Research and Public Health. - 16 : 11 (2019), p. 1-14. -
További szerzők:Nemieboka, Priscilla O. Njuguna, Diana Wangeshi (1983-) Ahadji, Makafui N. Kölesné Dezső Dóra (1985-) (orvos) Varga Orsolya (1977-) (orvos, jogász)
Pályázati támogatás:FOP-3.6.3-VEKOP-16-2017-00009
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