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001-es BibID:BIBFORM101778
035-os BibID:(Scopus)85129340914 (Wos)000790205000001
Első szerző:Kiss János (fizikus)
Cím:3D printed anthropomorphic left ventricular myocardial phantom for nuclear medicine imaging applications / János Kiss, László Balkay, Kornel Kukuts, Marton Miko, Attila Forgacs, Gyorgy Trencsenyi, Aron K. Krizsan
Dátum:2022
ISSN:2197-7364
Megjegyzések:Abstract Background: Anthropomorphic torso phantoms, including a cardiac insert, are frequently used to investigate the imaging performance of SPECT and PET systems. These phantom solutions are generally featuring a simple anatomical representation of the heart. 3D printing technology paves the way to create cardiac phantoms with more complex volume defnition. This study aimed to describe how a fllable left ventricular myocardium (LVm) phantom can be manufactured using geometry extracted from a patient image. Methods: The LVm of a healthy subject was segmented from 18F-FDG attenuation corrected PET image set. Two types of phantoms were created and 3D printed using polyethylene terephthalate glycol (PETG) material: one representing the original healthy LVm, and the other mimicking myocardium with a perfusion defect. The accuracy of the LVm phantom production was investigated by high-resolution CT scanning of 3 identical replicas. 99mTc SPECT acquisitions using local cardiac protocol were performed, without additional scattering media ("in air" measurements) for both phantom types. Furthermore, the healthy LVm phantom was inserted in the commercially available DataSpectrum Anthropomorphic Torso Phantom ("in torso" measurement) and measured with hot background and hot liver insert. Results: Phantoms were easy to fll without any air-bubbles or leakage, were found to be reproducible and fully compatible with the torso phantom. Seventeen segments polar map analysis of the "in air" measurements revealed that a signifcant defcit in the distribution appeared where it was expected. 59% of polar map segments had less than 5% deviation for the "in torso" and "in air" measurement comparison. Excluding the defcit area, neither comparison had more than a 12.4% deviation. All the three polar maps showed similar apex and apical region values for all confgurations. Conclusions: Fillable anthropomorphic 3D printed phantom of LVm can be produced with high precision and reproducibility. The 3D printed LVm phantoms were found to be suitable for SPECT image quality tests during diferent imaging scenarios. The fexibility of the 3D printing process presented in this study provides scalable and anthropomorphic image quality phantoms in nuclear cardiology imaging.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
3D nyomtatás
SPECT
Kardiológia
Tc-99m
Fantom
Megjelenés:EJNMMI Physics. - 9 : 1 (2022), p. 34. -
További szerzők:Balkay László (1963-) (biofizikus) Kukuts Kornél Mikó Márton (1990-) Forgács Attila (1985-) (fizikus) Trencsényi György (1978-) (biológus, biokémikus, molekuláris biológus) Krizsán Áron Krisztián (1986-) (fizikus)
Pályázati támogatás:TKP2020-NKA-04
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001-es BibID:BIBFORM103797
035-os BibID:(cikkazonosító)2196 (WoS)000858142400001 (Scopus)85138630573
Első szerző:Veres Gergő (radiográfus, biológus)
Cím:Phantom Study on the Robustness of MR Radiomics Features : comparing the Applicability of 3D Printed and Biological Phantoms / Veres Gergő, Kiss János, Vas Norman Félix, Kallos-Balogh Piroska, Máthé Nóra Beatrix, Lassen Martin Lyngby, Berényi Ervin, Balkay László
Dátum:2022
ISSN:2075-4418
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Diagnostics. - 12 : 9 (2022), p. 1-24. -
További szerzők:Kiss János (1992-) (fizikus) Vas Norman Félix Kallos-Balogh Piroska (1996-) Máthé Nóra Beatrix Lassen, Martin Lyngby Berényi Ervin (1964-) (radiológus) Balkay László (1963-) (biofizikus)
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