Összesen 3 találat.


001-es BibID:BIBFORM028327
Első szerző:Czeglédy Judit (virológus)
Cím:Detection of human papillomavirus deoxyribonucleic acid in the female genital tract / Czeglédy J., Gergely L., Hernádi Z., Póka R.
Megjegyzések:A total of 336 biopsies, scrapes and exfoliated cells from the cervix and from the lower genital tract were screened for human papilloma (HP) viral sequences of types 6, 11, 16 and 18 by Southern blot, dot blot and filter in situ (FISH) hybridizations with cloned 32P-radiolabeled HPV DNA probes. The specimens included cervical intraepithelial neoplasias (CIN I-III), carcinoma in situ and invasive carcinoma of the cervix and vagina, adenocarcinomas, vulvar and vaginal condylomata acuminata and healthy epithelial samples. The oncogenic HPV 16 was found in 46% of the cervical carcinomas. Most of the type 16 occurrences (75%) represented the third stage of inoperable cases. Similarly, HPV 18 was also most frequently present in this stage as well as in carcinoma in situ and in CIN III (25%, 18%). At the same time, in condylomata acuminata, types 6 and 11 were detectable in 88.7% of cares. In all, 13.5% of the normal samples harboured HPV DNA.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
HPV vírus
0 (DNA, Viral)
DNA, Viral/*analysis
Genitalia, Female/*analysis/microbiology/pathology
Uterine Cervical Neoplasms/diagnosis/microbiology
egyetemen (Magyarországon) készült közlemény
Megjelenés:Medical Microbiology and Immunology. - 178 : 6 (1989), p. 309-314. -
További szerzők:Gergely Lajos (1940-) (szakorvos, klinikai mikrobiológus) Hernádi Zoltán (1948-) (szülész-nőgyógyász, klinikai onkológus) Póka Róbert (1960-) (szülész-nőgyógyász, klinikai onkológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat


001-es BibID:BIBFORM071312
Első szerző:Veress György (biológus, mikrobiológus)
Cím:Oral contraceptive use and human papillomavirus infection in women without abnormal cytological results / Veress György, Csiky-Mészáros Tibor, Czeglédy Judit, Gergely Lajos
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Medical Microbiology And Immunology 181 : 4 (1992), p. 181-189. -
További szerzők:Csiky-Mészáros Tibor Czeglédy Judit (1944-) (virológus) Gergely Lajos (1940-) (szakorvos, klinikai mikrobiológus)


001-es BibID:BIBFORM035767
Első szerző:Veress György (biológus, mikrobiológus)
Cím:Follow-up of human papillomavirus (HPV) DNA and local anti-HPV antibodies in cytologically normal pregnant women / Veress G., Csiky-Mészáros T., Kónya J., Czeglédy J., Gergely L.
Megjegyzések:The high level of progesterone during pregnancy may enhance the transcription and replication of genital human papillomaviruses (HPV) through the glucocorticoid/progesterone response element found in the long control region of the viral genome. In this study, cytologically and colposcopically healthy pregnant women were subjected to a follow-up examination. Samples from the uterine cervix were collected during early pregnancy (n = 39), in the third trimester (n = 31), and a few weeks after birth (n = 30). The presence of HPV DNA was detected by polymerase chain reaction (PCR), while local secretory anti-viral IgA antibodies were demonstrated by enzyme-linked immunosorbent assay using synthetic peptide antigens. Follow-up examination by PCR revealed HPV DNA persistence in 5 women. In 5 other cases, HPV positivity changed from negative to positive during the follow-up. There was 1 case which changed from positive to negative and 1 in which the HPV type changed during the study. Altogether, 12 of 39 women (31%) were shown to harbor HPV DNA at some time during follow-up. HPV DNA positivity increased from 18% during early pregnancy to 27% after birth (difference not significant). On the other hand, there was a significant rise in the level of local antibodies against HPV antigens (E2, E7, and L2) between samples collected in early pregnancy and those collected after birth (P < 0.0001). This may indicate the reactivation of genital HPV infections during late pregnancy.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Medical Microbiology and Immunology. - 185 : 3 (1996), p. 139-144. -
További szerzők:Csiky-Mészáros Tibor Kónya József (1964-) (szakorvos, klinikai mikrobiológus) Czeglédy Judit (1944-) (virológus) Gergely Lajos (1940-) (szakorvos, klinikai mikrobiológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
Rekordok letöltése1